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卢戈氏碘液可识别癌前病变中的发育异常组织：一项临床试验。

Lugol's iodine identifies dysplastic tissue in precancerous lesions: A clinical trial.

作者信息

Fatima Shereen, Basu Rajarshi, Hallur Neelakamal H

机构信息

Department of Oral and Maxillofacial Surgery, Al-Badar Dental College and Hospital, Gulbarga, Karnataka, India.

出版信息

Ann Maxillofac Surg. 2016 Jul-Dec;6(2):172-174. doi: 10.4103/2231-0746.200333.

DOI:10.4103/2231-0746.200333
PMID:28299253
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5343623/
Abstract

INTRODUCTION

Intraepithelial dysplasia, or "invisible" precancerous lesions, provides a challenge for visualization to the surgical team. The prognostic relevance of dysplasia and carcinoma at surgical margins is well documented.

MATERIALS AND METHODS

We evaluated the use of Lugol's iodine in visualizing the surgical margins of dysplastic tissue by an observational study of 100 patients having oral precancerous lesions between June 2013 and March 2016.

CONCLUSION

Lugol's iodine is a simple, inexpensive, and apparently effective means of diagnosing and visualizing the surgical margins of the dysplastic tissue in oral precancerous lesions.

摘要

引言

上皮内发育异常，即“隐匿性”癌前病变，给手术团队的可视化带来了挑战。发育异常和癌在手术切缘的预后相关性已有充分记录。

材料与方法

我们通过对2013年6月至2016年3月期间100例患有口腔癌前病变患者的观察性研究，评估了卢戈氏碘在可视化发育异常组织手术切缘方面的应用。

结论

卢戈氏碘是一种简单、廉价且明显有效的方法，可用于诊断和可视化口腔癌前病变中发育异常组织的手术切缘。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f53/5343623/bfe860d136e6/AMS-6-172-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f53/5343623/a53b439e07c2/AMS-6-172-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f53/5343623/e9892db28741/AMS-6-172-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f53/5343623/f93bb4c2a3e1/AMS-6-172-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f53/5343623/bfe860d136e6/AMS-6-172-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f53/5343623/a53b439e07c2/AMS-6-172-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f53/5343623/e9892db28741/AMS-6-172-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f53/5343623/f93bb4c2a3e1/AMS-6-172-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f53/5343623/bfe860d136e6/AMS-6-172-g005.jpg

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