Bouquot J E, Whitaker S B
Department of Oral Pathology, West Virginia University, School of Dentistry, WVU Health Sciences Center-North, Morgantown.
Quintessence Int. 1994 Feb;25(2):133-40.
The precancerous nature of the most common of chronic oral mucosal lesions, leukoplakia, is much better understood now than at any time since it was first brought to professional attention by Sir James Paget 143 years ago. Clinical research from the past decade now allows confident identification of high-risk features of oral leukoplakias and of those persons affected by them. This paper summarizes current understanding of this important disease and provides practical suggestions for appropriate management and classification of its various subtypes or "phases."
最常见的慢性口腔黏膜病变——白斑的癌前性质，如今比143年前詹姆斯·佩吉特爵士首次引起专业人士关注以来的任何时候都得到了更好的理解。过去十年的临床研究现在能够可靠地识别口腔白斑的高危特征以及受其影响的人群。本文总结了目前对这种重要疾病的认识，并为其各种亚型或“阶段”的适当管理和分类提供了实用建议。
