Gonzales Junior, Bhupathiraju N V S Dinesh K, Perea William, Chu Huong, Berisha Naxhije, Bueno Veronica, Dodic Naser, Rozenberg Julia, Greenbaum Nancy L, Drain Charles Michael
Department of Chemistry, Hunter College of the City University of New York, 695 Park Avenue, New York, New York 10065, USA.
Chem Commun (Camb). 2017 Mar 28;53(26):3773-3776. doi: 10.1039/c7cc01265a.
A multifunctional chlorin platform appended with four short polyethylene glycols and a carboxylate-linker allows rapid conjugation to biotargeting motifs such as proteins and oligonucleotides. The stability and photophysical properties of the chlorin enable development of diagnostics, imaging, molecular tracking, and theranostics.
一个连接有四个短聚乙二醇和一个羧酸盐连接基的多功能二氢卟吩平台能够快速与生物靶向基序(如蛋白质和寡核苷酸)结合。二氢卟吩的稳定性和光物理性质有助于开发诊断、成像、分子追踪和诊疗技术。