水螅形态发生突变体的分析：III. 大突变体和小突变体

Analysis of morphogenetic mutants of hydra : III.Maxi andMini.

作者信息

Schaller H C, Schmidt T, Flick K, Grimmelikhuijzen C J P

机构信息

European Molecular Biology Laboratory, Postfach 10.2209, D-6900, Heidelberg, Germany.

出版信息

Wilehm Roux Arch Dev Biol. 1977 Sep;183(3):215-222. doi: 10.1007/BF00867322.

DOI:10.1007/BF00867322

PMID:28305087

Abstract

Minis have a doubling time of 2.4 days,maxis of 8 days.Minis regenerate head and foot 5 h faster thanmaxis.Minis have fewer tentacles (4.6) per head thanmaxis (6.1).Inmini the concentration of the head activator is equal to that inHydraattenuata, but the concentration of the head inhibitor is reduced (2-fold in the head, 1.2-fold in the body). The concentrations of the foot factors are normal.Minis respond likeHydra attenuata to head activator, foot activator and foot inhibitor, but they are less sensitive to head inhibitorInmaxi the concentration of the head activator is higher than inmini (5-fold in the head, 10-fold in the body) and that of the head inhibitor is also higher (4-fold in the head, 5-fold in the body). The concentration of the foot inhibitor is normal, that of the foot activator is doubled.Maxis are insensitive to added head activator and less sensitive to added head inhibitor and foot inhibitor. Their response to foot activator is normal.

摘要

小型水螅的倍增时间为2.4天，大型水螅为8天。小型水螅再生头部和足部的时间比大型水螅快5小时。小型水螅每头的触手（4.6条）比大型水螅（6.1条）少。在小型水螅中，头部激活因子的浓度与细螅中的浓度相等，但头部抑制因子的浓度降低（头部降低2倍，身体降低1.2倍）。足部因子的浓度正常。小型水螅对头部激活因子、足部激活因子和足部抑制因子的反应与细螅相似，但它们对头部抑制因子不太敏感。在大型水螅中，头部激活因子的浓度高于小型水螅（头部高5倍，身体高10倍），头部抑制因子的浓度也更高（头部高4倍，身体高5倍）。足部抑制因子的浓度正常，足部激活因子的浓度加倍。大型水螅对添加的头部激活因子不敏感，对添加的头部抑制因子和足部抑制因子不太敏感。它们对足部激活因子的反应正常。