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水螅形态发生突变体的分析:III. 大突变体和小突变体

Analysis of morphogenetic mutants of hydra : III.Maxi andMini.

作者信息

Schaller H C, Schmidt T, Flick K, Grimmelikhuijzen C J P

机构信息

European Molecular Biology Laboratory, Postfach 10.2209, D-6900, Heidelberg, Germany.

出版信息

Wilehm Roux Arch Dev Biol. 1977 Sep;183(3):215-222. doi: 10.1007/BF00867322.

DOI:10.1007/BF00867322
PMID:28305087
Abstract

Minis have a doubling time of 2.4 days,maxis of 8 days.Minis regenerate head and foot 5 h faster thanmaxis.Minis have fewer tentacles (4.6) per head thanmaxis (6.1).Inmini the concentration of the head activator is equal to that inHydraattenuata, but the concentration of the head inhibitor is reduced (2-fold in the head, 1.2-fold in the body). The concentrations of the foot factors are normal.Minis respond likeHydra attenuata to head activator, foot activator and foot inhibitor, but they are less sensitive to head inhibitorInmaxi the concentration of the head activator is higher than inmini (5-fold in the head, 10-fold in the body) and that of the head inhibitor is also higher (4-fold in the head, 5-fold in the body). The concentration of the foot inhibitor is normal, that of the foot activator is doubled.Maxis are insensitive to added head activator and less sensitive to added head inhibitor and foot inhibitor. Their response to foot activator is normal.

摘要

小型水螅的倍增时间为2.4天,大型水螅为8天。小型水螅再生头部和足部的时间比大型水螅快5小时。小型水螅每头的触手(4.6条)比大型水螅(6.1条)少。在小型水螅中,头部激活因子的浓度与细螅中的浓度相等,但头部抑制因子的浓度降低(头部降低2倍,身体降低1.2倍)。足部因子的浓度正常。小型水螅对头部激活因子、足部激活因子和足部抑制因子的反应与细螅相似,但它们对头部抑制因子不太敏感。在大型水螅中,头部激活因子的浓度高于小型水螅(头部高5倍,身体高10倍),头部抑制因子的浓度也更高(头部高4倍,身体高5倍)。足部抑制因子的浓度正常,足部激活因子的浓度加倍。大型水螅对添加的头部激活因子不敏感,对添加的头部抑制因子和足部抑制因子不太敏感。它们对足部激活因子的反应正常。

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1
Analysis of morphogenetic mutants of hydra : III.Maxi andMini.水螅形态发生突变体的分析:III. 大突变体和小突变体
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Competition for factors and cellular resources as a principle of pattern formation in Hydra. I. Increase of the potentials for head and bud formation and rescue of the regeneration-deficient mutant reg-16 by treatment with diacylglycerol and arachidonic acid.水螅中作为模式形成原则的因子和细胞资源竞争。I. 通过用二酰甘油和花生四烯酸处理增加头部和芽形成的潜能并拯救再生缺陷型突变体reg-16。
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引用本文的文献

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The polymorphism of Hydra microsatellite sequences provides strain-specific signatures.水螅微卫星序列的多态性提供了菌株特异性特征。
PLoS One. 2020 Sep 28;15(9):e0230547. doi: 10.1371/journal.pone.0230547. eCollection 2020.
2
Analysis of morphogenetic mutants of hydra : IV.Reg-16, a mutant deficient in head regeneration.水螅形态发生突变体的分析:IV.Reg-16,一种头部再生缺陷的突变体。
Wilehm Roux Arch Dev Biol. 1981 Jul;190(4):191-196. doi: 10.1007/BF00848302.
3
The fractionation of aHydra-derived inhibitor into head and foot inhibitors may be an artefact.

本文引用的文献

1
Analysis of early stages of budding inHydra by means of an endogenous inhibitor.利用内源性抑制剂对水螅出芽早期阶段进行分析。
Wilehm Roux Arch Dev Biol. 1977 Jun;182(2):117-129. doi: 10.1007/BF00848052.
2
Analysis of morphogenetic mutants of hydra : I. TheAberrant.水螅形态发生突变体的分析:I. 异常突变体
Wilehm Roux Arch Dev Biol. 1977 Sep;183(3):193-206. doi: 10.1007/BF00867320.
将源自水螅的抑制剂分离为头部抑制剂和足部抑制剂可能是一种人为现象。
Wilehm Roux Arch Dev Biol. 1983 Nov;192(6):327-332. doi: 10.1007/BF00848812.