Peking University Sixth Hospital, 51 Hua Yuan Bei Road, Haidian District, Beijing 100191, China; Peking University Institute of Mental Health, 51 Hua Yuan Bei Road, Haidian District, Beijing 100191, China; Key Laboratory of Mental Health, Ministry of Health (Peking University), 51 Hua Yuan Bei Road, Haidian District, Beijing 100191, China; National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), 51 Hua Yuan Bei Road, Haidian District, Beijing 100191, China.
Beijing Anding Hospital, Capital Medical University, 5 An Kang Hu Tong, Xicheng district, Beijing 100088, China.
Psychiatry Res. 2017 Jun;252:319-324. doi: 10.1016/j.psychres.2017.03.021. Epub 2017 Mar 11.
Although cognitive symptoms are prevalent and negatively affect psychosocial functioning, they are not commonly assessed in clinical practice, particularly in China. Perceived Deficits Questionnaire for Depression (PDQ-D) provides a subjective measure of cognitive dysfunction. This study aimed to examine the psychometric properties of Chinese version of PDQ-D in patients with MDD. The study sample comprised of 129 patients with MDD and 128 community volunteers. All patients with MDD were assessed with PDQ-D, Sheehan Disability Scale (SDS), Work Productivity and Activity Impairment: Specific Health Problem (WPAI-SPH), Patient Health Questionnaire-9 item (PHQ-9), and Digit Symbol Substitution Test (DSST). Community volunteers were assessed with PDQ-D, PHQ-9 and DSST. The Chinese version of PDQ-D showed excellent internal consistency and test-retest reliability. Three factors were identified and together explained 62.48% of the total variance. Validity of the PDQ-D was supported by its significant correlations with self-reported impaired work productivity, disability in all sub-domains of SDS, along with significant difference between community volunteers and MDD patients in PDQ-D. The questionnaire also significantly correlated with PHQ-9, but no correlation between PDQ-D and DSST was found. The Chinese version of the PDQ-D was found to be psychometrically valid to evaluate subjective cognitive dysfunction in patients with MDD.
虽然认知症状普遍存在，并对社会心理功能产生负面影响，但在临床实践中，特别是在中国，它们通常未得到评估。抑郁认知缺陷问卷（PDQ-D）提供了一种认知功能障碍的主观测量方法。本研究旨在检验中文版 PDQ-D 在 MDD 患者中的心理测量特性。研究样本包括 129 名 MDD 患者和 128 名社区志愿者。所有 MDD 患者均接受 PDQ-D、Sheehan 残疾量表（SDS）、工作效率和活动障碍：特定健康问题（WPAI-SPH）、患者健康问卷-9 项（PHQ-9）和数字符号替代测试（DSST）评估。社区志愿者接受 PDQ-D、PHQ-9 和 DSST 评估。中文版 PDQ-D 表现出极好的内部一致性和重测信度。确定了三个因素，它们共同解释了总方差的 62.48%。PDQ-D 的有效性得到了支持，它与自我报告的工作效率受损、SDS 所有子领域的残疾以及社区志愿者和 MDD 患者之间的 PDQ-D 显著差异显著相关。该问卷还与 PHQ-9 显著相关，但 PDQ-D 与 DSST 之间没有相关性。中文版 PDQ-D 在评估 MDD 患者的主观认知功能方面具有良好的心理测量特性。
