3T下使用非直肠内线圈的双参数和多参数MRI在前列腺癌检测与定位中的应用
Biparametric Multiparametric MRI with Non-endorectal Coil at 3T in the Detection and Localization of Prostate Cancer.
作者信息
Scialpi Michele, Prosperi Enrico, D'Andrea Alfredo, Martorana Eugenio, Malaspina Corrado, Palumbo Barbara, Orlandi Agostino, Falcone Giuseppe, Milizia Michele, Mearini Luigi, Aisa Maria Cristina, Scialpi Pietro, DE Dominicis Carlo, Bianchi Giampaolo, Sidoni Angelo
机构信息
Division of Radiology 2 and Nuclear Medicine, S. Maria della Misericordia Hospital, Perugia University, Perugia, Italy
Section of Anatomic Pathology and Histology, Department of Surgical and Biomedical Sciences, S. Maria della Misericordia Hospital, Perugia University, Perugia, Italy.
出版信息
Anticancer Res. 2017 Mar;37(3):1263-1271. doi: 10.21873/anticanres.11443.
AIM
To assess the sensitivity of biparametric magnetic resonance imaging (bpMRI) with non-endorectal coil in the detection and localization of index (dominant) and non-index lesions in patients suspected of having prostate cancer.
PATIENTS AND METHODS
We carried-out a retrospective analysis of multiparametric MRI (mpMRI) of 41 patients who underwent radical prostatectomy. Results of MRI for detection and localization of index and non-index lesions were correlated with those of histology.
RESULTS
No statistically significant difference in size was seen between tumor lesion at histology and index lesion at MRI. In 41 patients, a total of 131 tumors were identified at histology, while bpMRI (T2-weighted and diffusion-weighted MRI) approach detected 181 lesions. bpMRI gave 27.6% false-positives and 3.3% false-negatives. Sensitivity in lesion detection by bpMRI increased with lesion size assuming high values for lesions ≥10 mm. For bpMRI and mpMRI, the sensitivity for detecting index lesions was the same and equal: 100% in the peripheral zone 97.6% and 94.7% in the entire prostate and transitional zone, respectively.
CONCLUSION
bpMRI can be used alternatively to mpMRI to detect and localize index prostate cancer.
目的
评估使用非直肠内线圈的双参数磁共振成像（bpMRI）在疑似前列腺癌患者中检测和定位索引（主要）及非索引病变的敏感性。
患者与方法
我们对41例行根治性前列腺切除术患者的多参数MRI（mpMRI）进行了回顾性分析。MRI检测和定位索引及非索引病变的结果与组织学结果相关。
结果
组织学肿瘤病变与MRI索引病变大小在统计学上无显著差异。41例患者组织学共发现131个肿瘤，而bpMRI（T2加权和扩散加权MRI）方法检测到181个病变。bpMRI的假阳性率为27.6%，假阴性率为3.3%。bpMRI检测病变的敏感性随病变大小增加，对于≥10 mm的病变敏感性较高。对于bpMRI和mpMRI，检测索引病变的敏感性相同，分别为：外周区100%，整个前列腺和移行区分别为97.6%和94.7%。
结论
bpMRI可替代mpMRI用于检测和定位索引性前列腺癌。
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