Chen Lili, Hao Yaru
School of Mechatronics & Vehicle Engineering, Chongqing Jiaotong University, Chongqing 400074, China; School of Chongqing Key Laboratory of Urban Rail Transit Vehicle System Integration and Control, Chongqing Jiaotong University, Chongqing 400074, China.
Comput Math Methods Med. 2017;2017:7949507. doi: 10.1155/2017/7949507. Epub 2017 Feb 19.
Preterm birth (PTB) is the leading cause of perinatal mortality and long-term morbidity, which results in significant health and economic problems. The early detection of PTB has great significance for its prevention. The electrohysterogram (EHG) related to uterine contraction is a noninvasive, real-time, and automatic novel technology which can be used to detect, diagnose, or predict PTB. This paper presents a method for feature extraction and classification of EHG between pregnancy and labour group, based on Hilbert-Huang transform (HHT) and extreme learning machine (ELM). For each sample, each channel was decomposed into a set of intrinsic mode functions (IMFs) using empirical mode decomposition (EMD). Then, the Hilbert transform was applied to IMF to obtain analytic function. The maximum amplitude of analytic function was extracted as feature. The identification model was constructed based on ELM. Experimental results reveal that the best classification performance of the proposed method can reach an accuracy of 88.00%, a sensitivity of 91.30%, and a specificity of 85.19%. The area under receiver operating characteristic (ROC) curve is 0.88. Finally, experimental results indicate that the method developed in this work could be effective in the classification of EHG between pregnancy and labour group.
早产(PTB)是围产期死亡率和长期发病率的主要原因,会导致重大的健康和经济问题。早产的早期检测对其预防具有重要意义。与子宫收缩相关的子宫电图(EHG)是一种无创、实时且自动的新技术,可用于检测、诊断或预测早产。本文提出了一种基于希尔伯特-黄变换(HHT)和极限学习机(ELM)的妊娠组和分娩组EHG特征提取与分类方法。对于每个样本,使用经验模态分解(EMD)将每个通道分解为一组固有模态函数(IMF)。然后,将希尔伯特变换应用于IMF以获得解析函数。提取解析函数的最大振幅作为特征。基于ELM构建识别模型。实验结果表明,该方法的最佳分类性能可达准确率88.00%、灵敏度91.30%、特异性85.19%。受试者工作特征(ROC)曲线下面积为0.88。最后,实验结果表明本文所开发的方法可有效用于妊娠组和分娩组EHG的分类。