Corten Lieselotte, Morrow Brenda M
Department of Health and Rehabilitation Sciences, Physiotherapy (Ms Corten), University of Cape Town, Observatory, South Africa; and School of Child and Adolescent Health, Paediatric Critical Care and Children's Heart Disease (Dr Morrow), University of Cape Town, Red Cross War Memorial Children's Hospital, Rondebosch, South Africa.
Pediatr Phys Ther. 2017 Apr;29(2):106-117. doi: 10.1097/PEP.0000000000000355.
Airway clearance is an essential part of the management of cystic fibrosis (CF) as it facilitates clearance of viscous pulmonary secretions. This review aimed to determine the effect of autogenic drainage (AD) and assisted autogenic drainage (AAD) compared with no, sham, or other types of airway clearance in children with CF.
Two pediatric randomized cross-over trials were identified on the use of AD in children with CF; no studies were available on the use of AAD. In one study AD had a positive influence on the Huang score, and is preferred over postural drainage in this population.
We could not determine the efficacy of AD and AAD in children with CF. We recommend the implementation of pediatric-specific randomized controlled trials with adequate sample sizes, appropriate clinical outcome measures, and analysis of adverse effects.
气道清理是囊性纤维化（CF）管理的重要组成部分，因为它有助于清除黏稠的肺部分泌物。本综述旨在确定与不进行气道清理、假操作或其他类型的气道清理相比，自主引流（AD）和辅助自主引流（AAD）对CF患儿的影响。
确定了两项关于在CF患儿中使用AD的儿科随机交叉试验；没有关于使用AAD的研究。在一项研究中，AD对黄氏评分有积极影响，并且在该人群中比体位引流更受青睐。
我们无法确定AD和AAD对CF患儿的疗效。我们建议开展具有足够样本量、适当临床结局指标并分析不良反应的儿科专用随机对照试验。
