Cahill Megan E, Yao Yi, Nock David, Armstrong Philip M, Andreadis Theodore G, Diuk-Wasser Maria A, Montgomery Ruth R
Emerg Infect Dis. 2017 Apr;23(4):708-710. doi: 10.3201/eid2304.161669.
West Nile virus (WNV) infection is mainly asymptomatic but can be severe in elderly persons. As part of studies on immunity and aging in Connecticut, USA, we detected WNV seroconversion in 8.5% of nonimmunosuppressed and 16.8% of immunosuppressed persons. Age was not a significant seroconversion factor. Our findings suggest that immune factors affect seroconversion.
西尼罗河病毒(WNV)感染大多无症状,但在老年人中可能较为严重。作为美国康涅狄格州关于免疫与衰老研究的一部分,我们在8.5%的非免疫抑制人群和16.8%的免疫抑制人群中检测到了西尼罗河病毒血清转化。年龄并非血清转化的显著因素。我们的研究结果表明免疫因素会影响血清转化。