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中国儿科 2 型糖尿病——大流行、进展和潜在解决方案。

Paediatric type 2 diabetes in China-Pandemic, progression, and potential solutions.

机构信息

The Children's Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, China.

出版信息

Pediatr Diabetes. 2018 Feb;19(1):27-35. doi: 10.1111/pedi.12517. Epub 2017 Mar 22.

DOI:10.1111/pedi.12517
PMID:28326652
Abstract

China is gradually taking its place as one of the world's economic giants and concurrently learning to cope with the burden of diseases that are more common in the developed world, such as paediatric type 2 diabetes mellitus. The prevalence of type 2 diabetes has been recently observed among children and adolescents in China; hence, there is a lack of information about the incidence, prevalence, pathogenesis, and pathophysiology of the disease. Diagnosis, treatment, and management have been standardized to a large degree, but there is still a need for data regarding optimal management protocols and how to achieve the best control over current state of the disease. The objective of this review is to consolidate the available information about paediatric diabetes, with a focus on the increasing prevalence of type 2 diabetes in Chinese youth. Here we emphasize the prevention strategies and have included literature with respect to pathogenesis, diagnosis, and treatment published in English and Chinese within the past 10 years.

摘要

中国正逐渐成为世界经济大国之一,同时也在学习应对发达国家更为常见的疾病负担,如儿童 2 型糖尿病。最近在中国儿童和青少年中观察到 2 型糖尿病的患病率有所上升;因此,关于该病的发病率、患病率、发病机制和病理生理学方面的信息较为缺乏。诊断、治疗和管理已在很大程度上标准化,但仍需要有关最佳管理方案的数据,以及如何实现对现有疾病状态的最佳控制。本综述的目的是整合有关儿科糖尿病的现有信息,重点关注中国青少年 2 型糖尿病患病率的上升。在这里,我们强调了预防策略,并纳入了过去 10 年中以中文和英文发表的有关发病机制、诊断和治疗的文献。

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