Bermejo-Cantarero Alberto, Álvarez-Bueno Celia, Martinez-Vizcaino Vicente, García-Hermoso Antonio, Torres-Costoso Ana Isabel, Sánchez-López Mairena
Health and Social Research Center, Universidad de Castilla-La Mancha, Cuenca Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Talca Laboratorio de Ciencias de la Actividad Física, el Deporte y la Salud, Facultad de Ciencias Médicas, Universidad de Santiago de Chile, USACH, Santiago, Chile School of Nursing and Physiotherapy, Universidad de Castilla-La Mancha, Toledo School of Education, Universidad de Castilla-La Mancha, Ciudad Real, Castilla-La Mancha, Spain.
Medicine (Baltimore). 2017 Mar;96(12):e6407. doi: 10.1097/MD.0000000000006407.
Health related quality of life (HRQoL) is a subjective, multidimensional and changing over time construct. When HRQoL is decreased, a child is less likely to be able to develop normally and mature into a healthy adult. Physical inactivity is a priority public health problem. Evidence suggests how even moderate levels of physical activity or high fitness levels are associated with benefits for the health in children and adolescents. The aims of this systematic review are to examine the evidence about the relationship between physical activity, sedentary behavior, and fitness with HRQoL, and estimate the effects of interventions that have tested the effectiveness of the increase of the physical activity, the improvement of the physical fitness or the avoidance of sedentary behaviors in HRQoL in healthy subjects aged under 18 years old.
This systematic review and meta-analysis protocol was conducted following the preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) statement. To identify relevant studies, the following electronic databases will be searched: MEDLINE, EMBASE, Cochrane Database, Web of Science, and PEDro. Reference lists of relevant studies will be examined for links to potential related articles. The methodological quality of the observational included studies will be scored using a quality assessment checklist. For the intervention studies, the risk of bias will be estimated using The Cochrane Collaboration tool for assessing risk of bias. Reviewers will determine whether a meta-analysis is possible when data have been extracted. If it is, subgroup analyses will be carried out by age and socioeconomic status, and by the different dimensions of the HRQoL. If is not possible, a descriptive analysis will be conducted.
To our knowledge, this systematic review and meta-analysis will be the first that synthesizes the existing results about the relationship between physical activity, sedentary behavior, physical fitness, and HRQoL, and the effect of physical activity interventions on HRQoL, in healthy subjects under 18 years old. This study will clarify this relationship and will provide evidence for decision-making. Limitations may include the quality of the selected studies and their characteristics. Only studies published in English and Spanish will be included.
PROSPERO CRD42015025823.
健康相关生活质量（HRQoL）是一个主观的、多维度的且随时间变化的概念。当健康相关生活质量下降时，儿童正常发育并成长为健康成年人的可能性就会降低。身体活动不足是一个重要的公共卫生问题。有证据表明，即使是适度的身体活动水平或较高的身体素质水平也与儿童和青少年的健康益处相关。本系统评价的目的是检验关于身体活动、久坐行为和身体素质与健康相关生活质量之间关系的证据，并评估那些测试了增加身体活动、改善身体素质或避免久坐行为对18岁以下健康受试者健康相关生活质量有效性的干预措施的效果。
本系统评价和荟萃分析方案是按照系统评价和荟萃分析方案的首选报告项目（PRISMA-P）声明进行的。为了识别相关研究，将检索以下电子数据库：MEDLINE、EMBASE、Cochrane数据库、科学引文索引和PEDro。将检查相关研究的参考文献列表，以查找与潜在相关文章的链接。将使用质量评估清单对纳入观察性研究的方法学质量进行评分。对于干预性研究，将使用Cochrane协作网评估偏倚风险的工具来估计偏倚风险。在提取数据后，综述作者将确定是否可以进行荟萃分析。如果可以，将按年龄和社会经济地位以及健康相关生活质量的不同维度进行亚组分析。如果无法进行荟萃分析，将进行描述性分析。
据我们所知，本系统评价和荟萃分析将是首个综合现有关于身体活动、久坐行为、身体素质与健康相关生活质量之间关系以及身体活动干预对健康相关生活质量影响的结果的研究，研究对象为18岁以下的健康受试者。本研究将阐明这种关系，并为决策提供证据。局限性可能包括所选研究的质量及其特征。仅纳入以英文和西班牙文发表的研究。
PROSPERO CRD420150
