Cooper Rachel, Huang Lei, Hardy Rebecca, Crainiceanu Adina, Harris Tamara, Schrack Jennifer A, Crainiceanu Ciprian, Kuh Diana
MRC Unit for Lifelong Health and Ageing at UCL, London.
Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
J Gerontol A Biol Sci Med Sci. 2017 Oct 1;72(10):1424-1430. doi: 10.1093/gerona/glw331.
The aim of this study was to investigate associations of current body mass index (BMI) and obesity history with daily patterns of physical activity.
At age 60-64, participants from a British birth cohort study wore accelerometers for 5 days. Accelerometry counts were log-transformed and mean log-counts were used to derive a summary variable indicating total daily log-activity counts. Among those with complete data (n = 1,388) the associations of current BMI and age of first obesity were examined with: (a) total daily log-activity counts and (b) total log-activity counts in four segments of the day.
Higher current BMI and younger age at obesity were strongly associated with lower levels of total daily activity at age 60-64 even after adjustment for sex, socioeconomic factors, and health status. The fully-adjusted mean difference in total daily log-activity counts was -581.7 (95% confidence interval: -757.2, -406.3) when comparing BMI ≥35 kg/m2 with <25 kg/m2, representing an 18.4% difference. Participants who had been obese since early adulthood had the lowest levels of activity (mean difference in total daily log-activity counts was -413.1 (-638.1, -188.2) when comparing those who were obese by age 26 or 36 with those who were never obese, representing a 13.1% difference).
Obese older adults may require targeted interventions and additional support to improve their daily activity levels. As younger generations with greater lifetime exposure to obesity reach old age the proportion of adults achieving sufficient levels of activity to realize its associated health benefits is likely to decline.
本研究旨在调查当前体重指数(BMI)和肥胖史与日常身体活动模式之间的关联。
在60 - 64岁时,来自一项英国出生队列研究的参与者佩戴加速度计5天。对加速度计计数进行对数转换,并使用平均对数计数得出一个汇总变量,以表明每日总对数活动计数。在具有完整数据的参与者(n = 1388)中,研究了当前BMI和首次肥胖年龄与以下因素的关联:(a)每日总对数活动计数,以及(b)一天中四个时间段的总对数活动计数。
即使在调整了性别、社会经济因素和健康状况后,60 - 64岁时较高的当前BMI和较早的肥胖年龄与较低的每日总活动水平密切相关。将BMI≥35 kg/m²与<25 kg/m²进行比较时,每日总对数活动计数的完全调整后平均差异为-581.7(95%置信区间:-757.2,-406.3),差异为18.4%。自成年早期就肥胖的参与者活动水平最低(将26岁或36岁时肥胖的人与从未肥胖的人进行比较时,每日总对数活动计数的平均差异为-413.1(-638.1,-188.2),差异为13.1%)。
肥胖的老年人可能需要有针对性的干预措施和额外支持来提高他们的日常活动水平。随着有更多肥胖经历的年轻一代步入老年,达到足够活动水平以实现其相关健康益处的成年人比例可能会下降。