Yu Hongjuan, Li Limin, Liu Chaojie, Huang Weidong, Zhou Jin, Fu Wenqi, Ma Yi, Li Si, Chang Yuying, Liu Guoxiang, Wu Qunhong
Department of Hematology, the First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, 150001, China.
School of Psychology and Public Health, La Trobe University, Melbourne, VIC, 3086, Australia.
Health Qual Life Outcomes. 2017 Mar 23;15(1):55. doi: 10.1186/s12955-017-0628-6.
The leukemia affects not only the quality of life (QOL) of patients with the disease but also that of their family caregivers (FCs). The research studies on QOL of FCs for leukemia patients are limited. This study aimed to evaluate the QOL of FCs for leukemia patients in Heilongjiang province, China.
A cross-sectional questionnaire survey was undertaken with 309 FCs for leukemia patients recruited from three hospitals in Heilongjiang province. The QOL of the participants was assessed using the Chinese version of WHOQOL-BREF. Multivariate regression models were established to determine the predictors of the QOL of FCs, including the socio-economic characteristics of patients and FCs, and the emotional distress, social support and family functions of FCs.
The FCs had low QOL scores in all four domains: 12.7 ± 2.8 for physical, 12.2 ± 2.5 for psychological, 13.2 ± 2.9 for social and 11.3 ± 2.5 for environment. Social support is a major predictor of the QOL of FCs, with a standardized β coefficient of "high support" ranging from 0.41 to 0.58 for the four domains, followed by family function (β = 0.37 ~ 0.44 for psychological, social and environmental domains). The FCs who were older, highly educated, had no religious belief, suffered from a higher level of emotional distress, and provided care to younger patients and the patients without insurance coverage had lower QOL than the others.
The study provides some important insights into the QOL of FCs for leukemia patients. The QOL of FCs for leukemia patients is low and low levels of support to FCs are a major predictor of low QOL of FCs.
白血病不仅会影响患者的生活质量（QOL），还会影响其家庭照顾者（FCs）的生活质量。关于白血病患者家庭照顾者生活质量的研究有限。本研究旨在评估中国黑龙江省白血病患者家庭照顾者的生活质量。
对从黑龙江省三家医院招募的309名白血病患者家庭照顾者进行了横断面问卷调查。使用中文版的世界卫生组织生活质量简表（WHOQOL-BREF）评估参与者的生活质量。建立多变量回归模型以确定家庭照顾者生活质量的预测因素，包括患者和家庭照顾者的社会经济特征，以及家庭照顾者的情绪困扰、社会支持和家庭功能。
家庭照顾者在所有四个领域的生活质量得分都很低：身体领域为12.7±2.8，心理领域为12.2±2.5，社会领域为13.2±2.9，环境领域为11.3±2.5。社会支持是家庭照顾者生活质量的主要预测因素，“高支持”的标准化β系数在四个领域中为0.41至0.58，其次是家庭功能（心理、社会和环境领域的β=0.37至0.44）。年龄较大、受过高等教育、没有宗教信仰、情绪困扰程度较高、照顾年轻患者以及照顾没有保险的患者的家庭照顾者的生活质量低于其他人。
该研究为白血病患者家庭照顾者的生活质量提供了一些重要见解。白血病患者家庭照顾者的生活质量较低，对家庭照顾者的低水平支持是其生活质量低的主要预测因素。
