Rivero Alexander, Tang Christopher G, Rasgon Barry M
Head and Neck Surgeon at the Oakland Medical Center in CA.
Head and Neck Surgeon at the San Francisco Medical Center in CA.
Perm J. 2017;21:16-042. doi: 10.7812/TPP/16-042. Epub 2017 Mar 10.
We describe the first known case of bilateral basaloid squamous cell carcinoma of the parotid gland, and we review existing literature.
A previously healthy, 70-year-old white man presented with a 2-cm enlarging mass in the tail of the right parotid gland. Magnetic resonance imaging and computed tomography showed ipsilateral pathologic adenopathy. Results of fine-needle aspiration revealed a high-grade malignancy with squamous features. The patient underwent a right total parotidectomy and modified radical neck dissection. Final pathologic findings revealed a basaloid squamous cell carcinoma. Four years after the initial resection, the patient presented with an enlarging left parotid mass. Findings of fine-needle aspiration and imaging were similar to those 4 years earlier. The patient received a left total parotidectomy and modified radical neck dissection. Postoperative radiation therapy was performed after each surgical intervention. He remains disease free at 4-year follow-up after the second mass was resected.
Squamous cell carcinoma with basaloid features is a rare and aggressive type of squamous cell carcinoma. To our knowledge, this is the first case report of bilateral parotid basaloid squamous cell carcinoma.
我们描述了首例已知的双侧腮腺基底样鳞状细胞癌病例,并对现有文献进行了综述。
一名70岁的白人男性,既往身体健康,因右侧腮腺尾部出现一个2厘米大小且不断增大的肿块前来就诊。磁共振成像和计算机断层扫描显示同侧有病理淋巴结肿大。细针穿刺结果显示为具有鳞状特征的高级别恶性肿瘤。患者接受了右侧全腮腺切除术和改良根治性颈清扫术。最终病理结果显示为基底样鳞状细胞癌。初次切除术后四年,患者左侧腮腺出现肿块且不断增大。细针穿刺和影像学检查结果与四年前相似。患者接受了左侧全腮腺切除术和改良根治性颈清扫术。每次手术干预后均进行了术后放疗。在切除第二个肿块后的4年随访中,他仍无疾病复发。
具有基底样特征的鳞状细胞癌是一种罕见且侵袭性强的鳞状细胞癌类型。据我们所知,这是双侧腮腺基底样鳞状细胞癌的首例病例报告。