Brief Funct Genomics. 2017 Sep 1;16(5):249-273. doi: 10.1093/bfgp/elw042.
Since the discovery of microRNAs (miRNAs), a class of noncoding RNAs that regulate the gene expression posttranscriptionally in sequence-specific manner, there has been a release of number of tools useful for both basic and advanced applications. This is because of the significance of miRNAs in many pathophysiological conditions including cancer. Numerous bioinformatics tools that have been developed for miRNA analysis have their utility for detection, expression, function, target prediction and many other related features. This review provides a comprehensive assessment of web-based tools for the miRNA analysis that does not require prior knowledge of any computing languages.
自 microRNAs（miRNAs）被发现以来，作为一类非编码 RNA，可以通过序列特异性方式在转录后调控基因表达，已经有许多工具被开发出来，可用于基础和高级应用。这是因为 miRNAs 在许多病理生理条件下都具有重要意义，包括癌症。已经开发出许多用于 miRNA 分析的生物信息学工具，它们可用于检测、表达、功能、靶标预测和许多其他相关特征。本文综述了无需任何计算语言知识即可用于 miRNA 分析的基于网络的工具，并对其进行了全面评估。
