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Viral and bacterial infection in acute asthma and chronic obstructive pulmonary disease increases the risk of readmission.病毒和细菌感染在急性哮喘和慢性阻塞性肺疾病中会增加再次入院的风险。
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Human rhinovirus C infections mirror those of human rhinovirus A in children with community-acquired pneumonia.人类鼻病毒 C 感染与社区获得性肺炎患儿中的人类鼻病毒 A 感染相似。
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Phylogenetic analysis of human rhinovirus capsid protein VP1 and 2A protease coding sequences confirms shared genus-like relationships with human enteroviruses.人鼻病毒衣壳蛋白VP1和2A蛋白酶编码序列的系统发育分析证实了与人类肠道病毒存在类似的共同属关系。
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人鼻病毒A22型兰开斯特/2015株的基因组序列

Genome Sequence of Human Rhinovirus A22, Strain Lancaster/2015.

作者信息

Atkinson Kate V, Bishop Lisa A, Rhodes Glenn, Salez Nicolas, McEwan Neil R, Hegarty Matthew J, Robey Julie, Harding Nicola, Wetherell Simon, Lauder Robert M, Pickup Roger W, Wilkinson Mark, Gatherer Derek

机构信息

Division of Biomedical & Life Sciences, Faculty of Health & Medicine, Lancaster University, Lancaster, United Kingdom.

Royal Lancaster Infirmary, Lancaster, United Kingdom.

出版信息

Genome Announc. 2017 Mar 23;5(12):e01713-16. doi: 10.1128/genomeA.01713-16.

DOI:10.1128/genomeA.01713-16
PMID:28336607
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5364232/
Abstract

The genome of human rhinovirus A22 (HRV-A22) was assembled by deep sequencing RNA samples from nasopharyngeal swabs. The assembled genome is 8.7% divergent from the HRV-A22 reference strain over its full length, and it is only the second full-length genome sequence for HRV-A22. The new strain is designated strain HRV-A22/Lancaster/2015.

摘要

通过对鼻咽拭子的RNA样本进行深度测序,组装出了人鼻病毒A22(HRV-A22)的基因组。组装出的基因组与HRV-A22参考毒株在全长上有8.7%的差异,并且它是HRV-A22的第二个全长基因组序列。该新毒株被命名为HRV-A22/Lancaster/2015毒株。