Toval Angel, Baños Raúl, De la Cruz Ernesto, Morales-Delgado Nicanor, Pallarés Jesús G, Ayad Abdelmalik, Tseng Kuei Y, Ferran Jose L
Department of Human Anatomy and Psychobiology, School of Medicine, University of MurciaMurcia, Spain; Institute of Biomedical Research of Murcia (IMIB), Virgen de la Arrixaca University Hospital, University of MurciaMurcia, Spain.
Department of Physical Activity and Sport, Faculty of Sport Science, University of Murcia Murcia, Spain.
Front Behav Neurosci. 2017 Mar 8;11:42. doi: 10.3389/fnbeh.2017.00042. eCollection 2017.
Increasing evidence supports that physical activity promotes mental health; and regular exercise may confer positive effects in neurological disorders. There is growing number of reports that requires the analysis of the impact of physical activity in animal models. Exercise in rodents can be performed under voluntary or forced conditions. The former presents the disadvantage that the volume and intensity of exercise varies from subject to subject. On the other hand, a major challenge of the forced training protocol is the low level of performance typically achieved within a given session. Thus, the aim of the present study was to evaluate the effectiveness of gradual increasing of the volume and intensity (training habituation protocol) to improve the locomotor performance in a forced running-wheel system in rats. Sprague-Dawley rats were randomly assigned to either a group that received an exercise training habituation protocol, or a control group. The locomotor performance during forced running was assessed by an incremental exercise test. The experimental results reveal that the total running time and the distance covered by habituated rats was significantly higher than in control ones. We conclude that the exercise habituation protocol improves the locomotor performance in forced running wheels.
越来越多的证据表明，体育活动能促进心理健康；定期锻炼可能对神经疾病产生积极影响。越来越多的报告需要分析体育活动在动物模型中的影响。啮齿动物的运动可以在自愿或强制条件下进行。前者的缺点是运动的量和强度因个体而异。另一方面，强制训练方案的一个主要挑战是在给定的训练时段内通常达到的表现水平较低。因此，本研究的目的是评估在大鼠强迫跑步轮系统中逐渐增加运动量和强度（训练适应方案）以提高运动表现的有效性。将Sprague-Dawley大鼠随机分为接受运动训练适应方案的组或对照组。通过递增运动试验评估强迫跑步期间的运动表现。实验结果表明，适应训练的大鼠的总跑步时间和覆盖距离明显高于对照组。我们得出结论，运动适应方案可提高强迫跑步轮中的运动表现。
