Li Yunzhi, Dai Min, Peng Daiyin
a School of Pharmacy , Anhui University of Chinese Medicine , Hefei , P.R. China.
Nat Prod Res. 2017 Oct;31(20):2381-2386. doi: 10.1080/14786419.2017.1309531. Epub 2017 Mar 27.
The rhizomes of Atractylodes macrocephala are used as both a food source and traditional Chinese medicine in China. A phytochemical investigation was carried out on wild A. macrocephala grown in Qimen County in eastern China, and yielded a novel bisesquiterpenoid lactone, namely, biatractylenolide II (1), along with two known compounds, atractylenolide II (2) and taraxeryl acetate (3). The structure and relative configuration of the new compound were elucidated mainly by 1D and 2D NMR spectroscopic methods in combination with HRESIMS experiments. This paper describes the isolation and structural elucidation of the new bisesquiterpenoid lactone (1).
在中国，白术的根茎既是一种食物来源，也是传统中药。对生长于中国东部祁门县的野生白术进行了植物化学研究，从中分离得到一个新的双倍半萜内酯，即白术双内酯II（1），以及两个已知化合物白术内酯II（2）和蒲公英赛醇乙酸酯（3）。主要通过一维和二维核磁共振光谱方法结合高分辨电喷雾电离质谱实验阐明了新化合物的结构和相对构型。本文描述了这种新的双倍半萜内酯（1）的分离与结构解析过程。
