泰国东北部腌制鱼中污染的致癌肝吸虫及其他物质。
Carcinogenic Liver Fluke and Others Contaminated in Pickled Fish of Northeastern Thailand.
作者信息
Aukkanimart Ratchadawan, Boonmars Thidarut, Sriraj Pranee, Sripan Panupan, Songsri Jiraporn, Ratanasuwan Panaratana, Laummaunwai Porntip, Suwanantrai Apiporn, Aunpromma Surasit, Khueangchaingkhwang Sukhonthip, Pumhirunroj Benjamabhorn, Artchayasawat Atchara, Khuntikeo Narong, Loilome Watcharin, Namwat Nisana, Yongvanit Puangrat, Boonjaraspinyo Sirintip
机构信息
Department of Thai Traditional Medicine, Faculty of Natural Resources, Rajamangala University of Technology Isan Sakonnakhon Campus, Sakon Nakhon 47160, Thailand.
Neglected, Zoonosis and Vector-Borne Disease Group, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand. Email:
出版信息
Asian Pac J Cancer Prev. 2017 Feb 1;18(2):529-533. doi: 10.22034/APJCP.2017.18.2.529.
Twenty provinces in northeastern Thailand were investigated for fluke metacercariae contamination in pickled fish, or pla-som, during January –June 2016. A total of 129 pickled fish shops were randomly chosen. Samples were digested with acid-pepsin and those found to be infected with metacercariae were fed to hamsters to test for metacercariae infectivity. The results demonstrated that only 20.2% of the pla-som samples were infected with fluke metacercariae (mc), at various levels (1 to 268 mc/kg). All recovered fluke metacercariae were inactive, degenerated and could not develop to adults in the animal model. In conclusion, the fluke mc infection status in pla-som was correlated with the prevalence of fluke infection in this region known for high O.viverrini and cholangiocarcinoma development. Clearly, systematic control of the fluke life cycle is needed. Whether pickling is an effective preventive measure needs further assessment.
2016年1月至6月期间，对泰国东北部的20个省份进行了调查，以了解腌制鱼（即pla-som）中的吸虫囊蚴污染情况。总共随机挑选了129家腌制鱼店。样本用酸-胃蛋白酶消化，将那些被发现感染囊蚴的样本喂给仓鼠，以测试囊蚴的感染性。结果表明，只有20.2%的pla-som样本感染了吸虫囊蚴（mc），感染程度各不相同（1至268个mc/kg）。所有回收的吸虫囊蚴均无活性、已退化，在动物模型中无法发育为成虫。总之，pla-som中的吸虫囊蚴感染状况与该地区较高的猫后睾吸虫感染率及胆管癌发病率相关。显然，需要对吸虫的生命周期进行系统控制。腌制是否是一种有效的预防措施需要进一步评估。
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