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海洋生物技术中的酶促过程

Enzymatic Processes in Marine Biotechnology.

作者信息

Trincone Antonio

机构信息

Istituto di Chimica Biomolecolare, Consiglio Nazionale delle Ricerche, Via Campi Flegrei, 34, 80078 Pozzuoli, Naples, Italy.

出版信息

Mar Drugs. 2017 Mar 25;15(4):93. doi: 10.3390/md15040093.

Abstract

In previous review articles the attention of the biocatalytically oriented scientific community towards the marine environment as a source of biocatalysts focused on the habitat-related properties of marine enzymes. Updates have already appeared in the literature, including marine examples of oxidoreductases, hydrolases, transferases, isomerases, ligases, and lyases ready for food and pharmaceutical applications. Here a new approach for searching the literature and presenting a more refined analysis is adopted with respect to previous surveys, centering the attention on the enzymatic process rather than on a single novel activity. Fields of applications are easily individuated: (i) the biorefinery value-chain, where the provision of biomass is one of the most important aspects, with aquaculture as the prominent sector; (ii) the food industry, where the interest in the marine domain is similarly developed to deal with the enzymatic procedures adopted in food manipulation; (iii) the selective and easy extraction/modification of structurally complex marine molecules, where enzymatic treatments are a recognized tool to improve efficiency and selectivity; and (iv) marine biomarkers and derived applications (bioremediation) in pollution monitoring are also included in that these studies could be of high significance for the appreciation of marine bioprocesses.

摘要

在以往的综述文章中,以生物催化为导向的科学界将海洋环境视为生物催化剂来源,关注点集中在海洋酶与栖息地相关的特性上。文献中已有更新内容,包括可用于食品和制药应用的氧化还原酶、水解酶、转移酶、异构酶、连接酶和裂解酶的海洋实例。在此,相对于以往的调查,采用了一种新的文献检索方法并进行更精细的分析,将注意力集中在酶促过程而非单一的新活性上。应用领域很容易确定:(i)生物精炼价值链,其中生物质的供应是最重要的方面之一,水产养殖是突出的领域;(ii)食品工业,对海洋领域的兴趣同样得到发展,以处理食品加工中采用的酶促程序;(iii)对结构复杂的海洋分子进行选择性且简便的提取/修饰,其中酶处理是提高效率和选择性的公认工具;(iv)海洋生物标志物及其在污染监测中的衍生应用(生物修复)也包括在内,因为这些研究对于理解海洋生物过程可能具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f43/5408239/ed5e8fa31bad/marinedrugs-15-00093-g001.jpg

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