Trincone Antonio
Istituto di Chimica Biomolecolare, Consiglio Nazionale delle Ricerche, Via Campi Flegrei, 34, 80078 Pozzuoli, Naples, Italy.
Mar Drugs. 2017 Mar 25;15(4):93. doi: 10.3390/md15040093.
In previous review articles the attention of the biocatalytically oriented scientific community towards the marine environment as a source of biocatalysts focused on the habitat-related properties of marine enzymes. Updates have already appeared in the literature, including marine examples of oxidoreductases, hydrolases, transferases, isomerases, ligases, and lyases ready for food and pharmaceutical applications. Here a new approach for searching the literature and presenting a more refined analysis is adopted with respect to previous surveys, centering the attention on the enzymatic process rather than on a single novel activity. Fields of applications are easily individuated: (i) the biorefinery value-chain, where the provision of biomass is one of the most important aspects, with aquaculture as the prominent sector; (ii) the food industry, where the interest in the marine domain is similarly developed to deal with the enzymatic procedures adopted in food manipulation; (iii) the selective and easy extraction/modification of structurally complex marine molecules, where enzymatic treatments are a recognized tool to improve efficiency and selectivity; and (iv) marine biomarkers and derived applications (bioremediation) in pollution monitoring are also included in that these studies could be of high significance for the appreciation of marine bioprocesses.
在以往的综述文章中,以生物催化为导向的科学界将海洋环境视为生物催化剂来源,关注点集中在海洋酶与栖息地相关的特性上。文献中已有更新内容,包括可用于食品和制药应用的氧化还原酶、水解酶、转移酶、异构酶、连接酶和裂解酶的海洋实例。在此,相对于以往的调查,采用了一种新的文献检索方法并进行更精细的分析,将注意力集中在酶促过程而非单一的新活性上。应用领域很容易确定:(i)生物精炼价值链,其中生物质的供应是最重要的方面之一,水产养殖是突出的领域;(ii)食品工业,对海洋领域的兴趣同样得到发展,以处理食品加工中采用的酶促程序;(iii)对结构复杂的海洋分子进行选择性且简便的提取/修饰,其中酶处理是提高效率和选择性的公认工具;(iv)海洋生物标志物及其在污染监测中的衍生应用(生物修复)也包括在内,因为这些研究对于理解海洋生物过程可能具有重要意义。