Yildirim Mine, Kilic Deniz, Dursun Mehmet Emin, Dursun Birgul
Department of Ophthalmology, Gazi Yasargil Training and Research Hospital, Diyarbakır, Turkey.
Int Med Case Rep J. 2017 Mar 22;10:99-103. doi: 10.2147/IMCRJ.S132479. eCollection 2017.
In this report, we present a case of diabetic papillopathy that resolved after a single dose of intravitreal ranibizumab injection. A 50-year-old male presented with painless visual loss in his right eye. His visual acuity was 1/10 in the right eye and 10/10 in the left eye. Anterior segment examination of both eyes was unremarkable. Posterior segment of the right eye showed nonproliferative diabetic retinopathy with a swollen optic disc. Fluorescein angiography and optical coherence tomography were performed. There was dye leakage from the right optic disc. Optical coherence tomography revealed a significant increase in retinal nerve fiber layer thickness. Magnetic resonance imaging of the brain and orbit were normal. The patient received a single intravitreal ranibizumab (0.5 mg) injection. Two weeks after the injection, there was a marked regression of the disc swelling. Three months after the injection the optic disc was pallor and visual acuity was 6/10.
在本报告中，我们呈现了一例经单次玻璃体内注射雷珠单抗后病情缓解的糖尿病性视乳头病变病例。一名50岁男性因右眼无痛性视力丧失就诊。其右眼视力为1/10，左眼视力为10/10。双眼眼前节检查未见明显异常。右眼后节显示非增殖性糖尿病视网膜病变伴视盘肿胀。进行了荧光素血管造影和光学相干断层扫描。右眼视盘有染料渗漏。光学相干断层扫描显示视网膜神经纤维层厚度显著增加。脑部和眼眶的磁共振成像正常。该患者接受了单次玻璃体内注射雷珠单抗（0.5毫克）。注射后两周，视盘肿胀明显消退。注射后三个月，视盘苍白，视力为6/10。
