Kim Moosang, Lee Jang-Hun, Lee Seung-Jun
Department of Ophthalmology, Kangwon National University, Chuncheon, South Korea.
Clin Ophthalmol. 2013;7:2257-60. doi: 10.2147/OPTH.S55076. Epub 2013 Nov 27.
We report a case of diabetic papillopathy that demonstrated a resolution of optic disk swelling and rapid visual recovery when intravitreal ranibizumab was administered. A 51-year-old male presented with acute painless visual loss in his right eye. His vision was 20/320 in the right eye and 20/50 in the left eye. Fundus examination of the right eye showed nonproliferative diabetic retinopathy with macular edema and a swollen optic disk. Fluorescein angiography showed dye leakage from the right optic disk. Optical coherent tomography revealed a significant increase in retinal nerve fiber-layer thickness. Magnetic resonance imaging of the brain was normal. The patient received a single intravitreal ranibizumab (0.5 mg) injection. Two weeks following injection, there was marked regression of the disk swelling and improvement of macular edema, with vision improving to 20/100. Three months following injection, there was complete resolution of the optic disk swelling. No further treatment was required.
我们报告一例糖尿病性视乳头病变，玻璃体腔内注射雷珠单抗后，视盘肿胀消退且视力迅速恢复。一名51岁男性因右眼急性无痛性视力丧失就诊。右眼视力为20/320，左眼视力为20/50。右眼眼底检查显示非增殖性糖尿病视网膜病变伴黄斑水肿及视盘肿胀。荧光素血管造影显示右眼视盘有染料渗漏。光学相干断层扫描显示视网膜神经纤维层厚度显著增加。脑部磁共振成像正常。患者接受了一次玻璃体腔内雷珠单抗（0.5毫克）注射。注射后两周，视盘肿胀明显消退，黄斑水肿改善，视力提高到20/100。注射后三个月，视盘肿胀完全消退，无需进一步治疗。
