Rössner S, Andersson I L, Ryttig K
Department of Internal Medicine, Gustaf V Research Institute, Karolinska Hospital, Stockholm, Sweden.
Acta Med Scand. 1988;223(4):353-7. doi: 10.1111/j.0954-6820.1988.tb15884.x.
Sixty-two moderately obese (body mass index = 34.8), but normotensive females were treated with a balanced hypocaloric diet providing 1,600 kcal/day and either a 6.5 g dietary fibre supplement or placebo in a randomized, double-blind, parallel group design. During a 12-week treatment programme, weight loss was similar in both groups (4.1 and 4.4 kg, respectively). Initially the blood pressure was 123/76 mmHg in the fibre group compared with 124/74 mmHg in the placebo group (p less than 0.05). In the fibre-treated group a significant fall in diastolic blood pressure by 4 mmHg was found (p less than 0.05). No significant change was seen in the placebo group. It is suggested that dietary fibre may affect blood pressure independently of weight change.
62名中度肥胖（体重指数=34.8）但血压正常的女性，采用提供1600千卡/天的均衡低热量饮食，并在随机、双盲、平行组设计中，给予6.5克膳食纤维补充剂或安慰剂。在为期12周的治疗方案中，两组体重减轻情况相似（分别为4.1千克和4.4千克）。最初，纤维组血压为123/76毫米汞柱，而安慰剂组为124/74毫米汞柱（p<0.05）。在纤维治疗组中，舒张压显著下降了4毫米汞柱（p<0.05）。安慰剂组未见显著变化。提示膳食纤维可能独立于体重变化影响血压。
