Atmaca Murat Mert, Altiokka Uzun Güneş, Shugaiv Erkingül, Kürtüncü Murat, Eraksoy Mefküre
Department of Neurology, İstanbul University İstanbul Faculty of Medicine, İstanbul, Turkey.
Clinic of Neurology, Tokat State Hospital, Tokat, Turkey.
Noro Psikiyatr Ars. 2015 Sep;52(3):315-318. doi: 10.5152/npa.2015.8725. Epub 2015 Jul 7.
Neurological complications of inflammatory bowel diseases (i.e., ulcerative colitis and Crohn's disease) can be summarized as a combination of neuromuscular manifestations, cerebrovascular and demyelinating diseases that can be seen in approximately 3% of patients. In addition, asymptomatic cerebral white matter lesions may be detected in these patients. Clustering of diseases within families may be explained by the exposure to similar environmental factors, shared genes, or complex interactions between genetic and environmental factors. Here we report an epileptic patient with Crohn's disease and cerebral white matter lesions, a family with ulcerative colitis and multiple sclerosis and two patients who have both multiple sclerosis and Crohn's disease.
炎症性肠病（即溃疡性结肠炎和克罗恩病）的神经并发症可概括为神经肌肉表现、脑血管疾病和脱髓鞘疾病的组合，约3%的患者会出现这些情况。此外，这些患者可能检测出无症状性脑白质病变。家族性疾病聚集现象可能是由于暴露于相似环境因素、共享基因，或遗传与环境因素之间的复杂相互作用所致。在此，我们报告一名患有克罗恩病和脑白质病变的癫痫患者、一个患有溃疡性结肠炎和多发性硬化症的家庭，以及两名同时患有多发性硬化症和克罗恩病的患者。
