Caserta Carmelo Antonio, Mele Alfonso, Surace Pasquale, Ferrigno Luigina, Amante Angela, Messineo Arianna, Vacalebre Carmelo, Amato Fulvia, Baldassarre Damiano, Amato Mauro, Marcucci Fabrizio, Zuin Massimo
Associazione Calabrese di Epatologia/ACE, Pellaro, Reggio Calabria, Italy - UO Medicina, Policlinico Madonna della Consolazione, Reggio Calabria, Italy.
Associazione Calabrese di Epatologia/ACE, Pellaro, Reggio Calabria, Italy.
Ann Ist Super Sanita. 2017 Jan-Mar;53(1):77-81. doi: 10.4415/ANN_17_01_14.
The prevalence of risk factors for cardiovascular and metabolic diseases was investigated in an adult population of the city of Cittanova, Southern Italy.
The study was conducted among 992 randomly selected adults aged 18-75 years, between April 2009 and January 2011.
Prevalence rates of non-alcoholic fatty liver disease (NAFLD), overweight, obesity, and metabolic syndrome (MS) were 24.8%, 41.5%, 27.1%, and 34.4%, respectively. For the components of MS, prevalence of central obesity was 47.4%, impaired fasting glucose (IFG) 34.7%; hypertension 53.7%, low high-density lipoprotein (HDL) cholesterol 34.2%, and hypertriglyceridemia 27.2%.
Hypertension, central obesity, IFG, low HDL cholesterol, hypertriglyceridemia, MS, and increased carotid artery intima-media thickness (IMT) were significantly associated with NAFLD after adjustment for age and sex. With additional adjustment for body mass index (BMI), IMT and MS (depending on the prevalence ratio that was investigated), the positive association between the NAFLD and increased IMT lost statistical significance, while that with body mass index (BMI) and MS remained significant.
在意大利南部奇塔诺瓦市的成年人群中调查心血管和代谢疾病风险因素的患病率。
2009年4月至2011年1月期间，对992名随机选取的18 - 75岁成年人进行了研究。
非酒精性脂肪性肝病（NAFLD）、超重、肥胖和代谢综合征（MS）的患病率分别为24.8%、41.5%、27.1%和34.4%。对于MS的各组分，中心性肥胖患病率为47.4%，空腹血糖受损（IFG）为34.7%；高血压为53.7%，高密度脂蛋白（HDL）胆固醇降低为34.2%，高甘油三酯血症为27.2%。
在对年龄和性别进行调整后，高血压、中心性肥胖、IFG、HDL胆固醇降低、高甘油三酯血症、MS以及颈动脉内膜中层厚度（IMT）增加与NAFLD显著相关。在进一步对体重指数（BMI）、IMT和MS（取决于所研究的患病率比）进行调整后，NAFLD与IMT增加之间的正相关失去统计学意义，而与体重指数（BMI）和MS之间的相关性仍然显著。
