Collings Paul J, Ball Helen L, Santorelli Gillian, West Jane, Barber Sally E, McEachan Rosemary Rc, Wright John
Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK.
Parent-Infant Sleep Lab & Anthropology of Health Research Group, Department of Anthropology, Durham University, Durham.
Sleep. 2017 Feb 1;40(2). doi: 10.1093/sleep/zsw054.
To examine independent associations of sleep duration with total and abdominal adiposity, and the bidirectionality of these associations, in a young biethnic sample of children from a disadvantaged location.
Child sleep duration (h/day) was parent-reported by questionnaire and indices of total (body weight, body mass index, percent body fat (%BF), sum of skinfolds) and abdominal adiposity (waist circumference) were measured using standard anthropometric procedures at approximately 12, 18, 24, and 36 months of age in 1,338 children (58% South Asian; 42% White). Mixed effects models were used to quantify independent associations (expressed as standardised β-coefficients (95% confidence interval (CI)) of sleep duration with adiposity indices using data from all four time-points. Factors considered for adjustment in models included basic demographics, pregnancy and birth characteristics, and lifestyle behaviours.
With the exception of the sum of skinfolds, sleep duration was inversely and independently associated with indices of total and abdominal adiposity in South Asian children. For example, one standard deviation (SD) higher sleep duration was associated with reduced %BF by -0.029 (95% CI: -0.053, -0.0043) SDs. Higher adiposity was also independently associated with shorter sleep duration in South Asian children (for example, %BF: β = -0.10 (-0.16, -0.028) SDs). There were no significant associations in White children.
Associations between sleep duration and adiposity are bidirectional and independent among South Asian children from a disadvantaged location. The results highlight the importance of considering adiposity as both a determinant of decreased sleep and a potential consequence.
在来自弱势地区的双族裔儿童样本中，研究睡眠时间与总体肥胖和腹部肥胖之间的独立关联，以及这些关联的双向性。
通过问卷由家长报告儿童睡眠时间（小时/天），并在1338名儿童（58%为南亚裔；42%为白人）12、18、24和36个月大时，使用标准人体测量程序测量总体肥胖指标（体重、体重指数、体脂百分比（%BF）、皮褶厚度总和）和腹部肥胖指标（腰围）。使用混合效应模型，利用所有四个时间点的数据，量化睡眠时间与肥胖指标之间的独立关联（以标准化β系数（95%置信区间（CI））表示）。模型中考虑的调整因素包括基本人口统计学特征、妊娠和出生特征以及生活方式行为。
除皮褶厚度总和外，南亚儿童的睡眠时间与总体肥胖和腹部肥胖指标呈负向且独立关联。例如，睡眠时间每增加一个标准差（SD），%BF降低-0.029（95%CI：-0.053，-0.0043）个标准差。较高的肥胖程度也与南亚儿童较短的睡眠时间独立相关（例如，%BF：β=-0.10（-0.16，-0.028）个标准差）。白人儿童中未发现显著关联。
在来自弱势地区的南亚儿童中，睡眠时间与肥胖之间的关联是双向且独立的。结果强调了将肥胖视为睡眠减少的决定因素和潜在后果的重要性。
