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老年人心力衰竭的患病率及未来预测:AGES-雷克雅未克研究

Prevalence of heart failure in the elderly and future projections: the AGES-Reykjavík study.

作者信息

Danielsen Ragnar, Thorgeirsson Gudmundur, Einarsson Haukur, Ólafsson Örn, Aspelund Thor, Harris Tamara B, Launer Lenore, Gudnason Vilmundur

机构信息

a The Department of Cardiology , Landspítali University Hospital , Reykjavík , Iceland.

c The University of Iceland , Reykjavík , Iceland.

出版信息

Scand Cardiovasc J. 2017 Aug;51(4):183-189. doi: 10.1080/14017431.2017.1311023. Epub 2017 Apr 3.

Abstract

OBJECTIVES

To assess the prevalence of heart failure (HF) in a randomly selected study population of elderly individuals representing the general population of Iceland. Furthermore, to project the number of individuals likely to have HF in the future.

DESIGN

Baseline characteristics and clinical data from 5706 individuals who participated in the population based AGES-Reykjavik Study and gave their informed consent were used. Their age range was 66-98 years (mean age 77.0 ± 5.9 years), 57.6% were females. HF-diagnoses were established by review of hospital records and adjudicated according to prespecified criteria. Data from the 'Statistics Iceland' institution on the current size, age and sex distribution of the population and its prediction into the sixth decade were also used.

RESULTS

The prevalence of HF was 3.6% in the sexes combined, but higher in men (5.1%) than women (2.7%) (p < .001). The prevalence of HF per age groups ≤69, 70-74, 75-79, 80-84 and ≥85 years was 1.7%, 1.5%, 3.7%, 5.2% and 7.2%, respectively. The number of individuals ≥70 years with HF will increase considerably in the future. Thus, a calculation based on the projected age distribution and increase in the number of elderly ≥70 years in the coming decades, demonstrated that the number of patients with HF will have increased 2.3-fold by the year 2040 and tripled by the year 2060.

CONCLUSIONS

This study, in a cohort of elderly participants representative of the general population in a Nordic country, predicts that HF will be a major and increasing health problem in the coming decades.

摘要

目的

评估在冰岛一般人群中随机抽取的老年研究人群中心力衰竭(HF)的患病率。此外,预测未来可能患HF的人数。

设计

使用了5706名参与基于人群的AGES-雷克雅未克研究并给予知情同意者的基线特征和临床数据。他们的年龄范围为66 - 98岁(平均年龄77.0±5.9岁),女性占57.6%。通过查阅医院记录确定HF诊断,并根据预先设定的标准进行判定。还使用了冰岛统计局关于当前人口规模、年龄和性别分布及其到第六个十年的预测数据。

结果

男女合并的HF患病率为3.6%,但男性(5.1%)高于女性(2.7%)(p < 0.001)。年龄≤69岁、70 - 74岁、75 - 79岁、80 - 84岁和≥85岁各年龄组的HF患病率分别为1.7%、1.5%、3.7%、%和7.2%。未来≥70岁患HF的人数将大幅增加。因此,根据预测的年龄分布以及未来几十年≥70岁老年人数量的增加进行计算表明,到2040年HF患者数量将增加2.3倍,到2060年将增加两倍。

结论

这项在代表北欧国家一般人群的老年参与者队列中的研究预测,在未来几十年中HF将成为一个主要且不断增加的健康问题。

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