Murray M J, Murray A B
Am J Clin Nutr. 1979 Mar;32(3):593-6. doi: 10.1093/ajcn/32.3.593.
The role of anorexia of infection as a mechanism of host defense was studied by force-feeding infected mice to a normal energy intake. Their mortality and survival times were then compared with those of infected mice feeding ad libitum. Mortality was increased and survival time shortened in force fed animals. Our observations suggest that anorexia, by reducing energy intake, has a significant role in the early defense of the host.
通过强制喂食感染小鼠使其达到正常能量摄入量,研究了感染性厌食作为宿主防御机制的作用。然后将它们的死亡率和存活时间与自由采食的感染小鼠进行比较。强制喂食的动物死亡率增加,存活时间缩短。我们的观察结果表明,厌食通过减少能量摄入,在宿主的早期防御中具有重要作用。