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与急性特发性盲点扩大相关的多发性一过性白点综合征(MEWDS)后复发性局灶性脉络膜挖空。

Recurrent focal choroidal excavation following multiple evanescent white dot syndrome (MEWDS) associated with acute idiopathic blind spot enlargement.

作者信息

Jabbarpoor Bonyadi Mohammad Hossein, Hassanpour Kiana, Soheilian Masoud

机构信息

Ophthalmic Research Center and Ophthalmology Department, Labbafinejad Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Int Ophthalmol. 2018 Apr;38(2):815-821. doi: 10.1007/s10792-017-0511-9. Epub 2017 Apr 3.

DOI:10.1007/s10792-017-0511-9
PMID:28374276
Abstract

PURPOSE

To present a recurrent case of conforming focal choroidal excavation (FCE) following multiple evanescent white dot syndrome (MEWDS) in a 25-year-old woman.

METHODS

Following spontaneous MEWDS sings resolution our patient noted a recurrent decrease in vision. Repeated OCT revealed elevation and mild disruption of RPE layer at fovea without previous angiographic MEWDS signs. At this time, short-term systemic steroid therapy was started and visual acuity became normal.

RESULTS

Following quiescence of the new-onset phase, the conforming type of FCE located in inferior macula appeared in OCT. In the following next 2 years recurrence of presumptive focal subfoveal choriocapillaritis occurred for three times presenting with blurred vision. During every acute attack, above-mentioned FCE disappeared and returned back again after resolution of presumptive focal choriocapillaritis.

CONCLUSIONS

This is the first and unique case of recurrent type of FCE following MEWDS. It seems to disappear during active phase of presumptive focal choriocapillaritis and then returns after the eye has become quiescent.

摘要

目的

报告一例25岁女性在多发性一过性白点综合征(MEWDS)后出现复发性一致性黄斑中心凹脉络膜凹陷(FCE)的病例。

方法

在MEWDS症状自发消退后,我们的患者视力再次下降。重复光学相干断层扫描(OCT)显示黄斑中心凹视网膜色素上皮(RPE)层抬高且轻度中断,此前血管造影未显示MEWDS征象。此时开始短期全身应用类固醇治疗,视力恢复正常。

结果

在新发病阶段静止后,OCT显示位于黄斑下的一致性FCE。在接下来的2年中,推测性黄斑中心凹下脉络膜毛细血管炎复发3次,伴有视力模糊。每次急性发作时,上述FCE消失,在推测性黄斑中心凹下脉络膜毛细血管炎消退后又再次出现。

结论

这是MEWDS后复发性FCE的首例独特病例。它似乎在推测性黄斑中心凹下脉络膜毛细血管炎的活动期消失,然后在眼部静止后再次出现。

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