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脉络膜空洞性疾病

Choroidal Cavitary Disorders.

作者信息

Nassar Sandra, Tarbett Aaron K, Browning David J

机构信息

Eye Department, Charlotte Eye, Ear, Nose, and Throat Associates, Charlotte, NC 28210, USA.

Eye Department, WG Hefner VA Medical System, Salisbury, NC 28144, USA.

出版信息

Clin Ophthalmol. 2020 Sep 8;14:2609-2623. doi: 10.2147/OPTH.S264731. eCollection 2020.

Abstract

The structure and functions of the choroid have been long acknowledged but the pathophysiology behind various anomalies has been difficult to understand until the advent of optical coherence tomography (OCT). With OCT imaging, choroidal cavitations appear as optically empty spaces between the outer retinal and choroidal layers with attenuation or loss of outer retinal layers. Choroidal cavitations are found in the posterior pole and seen in conditions such as pathologic myopia, north carolina macular dystrophy (NCMD), focal choroidal excavation (FCE), and torpedo maculopathy (TM). To date, these disorders have not been linked. A commonality they all share is malformation of the RPE-photoreceptor-choroid complex. The following report describes the differences and similarities of choroidal cavitation amongst the different retinal disorders and emphasizes the importance of multimodal imaging in the detection and management of potential complications.

摘要

脉络膜的结构和功能早已为人所知,但直到光学相干断层扫描(OCT)出现之前,各种异常背后的病理生理学一直难以理解。通过OCT成像,脉络膜空洞表现为视网膜外层和脉络膜层之间的光学空白区域,伴有视网膜外层的衰减或缺失。脉络膜空洞在后极部被发现,见于病理性近视、北卡罗来纳黄斑营养不良(NCMD)、局灶性脉络膜凹陷(FCE)和鱼雷性黄斑病变(TM)等情况。迄今为止,这些疾病尚未被联系起来。它们共有的一个共同点是视网膜色素上皮-光感受器-脉络膜复合体的畸形。以下报告描述了不同视网膜疾病中脉络膜空洞的差异和相似之处,并强调了多模态成像在检测和管理潜在并发症方面的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e6f/7490088/24d7d4e99910/OPTH-14-2609-g0001.jpg

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