Banik Anna, Schwarzer Ralf, Pawlowska Izabela, Boberska Monika, Cieslak Roman, Luszczynska Aleksandra
CARE-BEH Center for Applied Research on Health Behavior and Health, SWPS University of Social Sciences and Humanities, Wroclaw, Poland.
Department of Education and Psychology, Freie Universität Berlin, Berlin, Germany.
Health Qual Life Outcomes. 2017 Apr 4;15(1):62. doi: 10.1186/s12955-017-0645-5.
We investigated the determinants of trajectories of physical symptoms related to lung cancer (a quality of life [QOL] aspect) and self-efficacy among patients with non-small cell lung cancer (NSCLC). It was hypothesized that gender and family cancer history in first-degree relatives would have synergistic effects on QOL-lung cancer specific symptoms and self-efficacy. Women with family cancer history were expected to be at risk of poorer adjustment.
Quantitative, longitudinal design was applied. Participants provided their responses at 3-4 days after surgery, 1-month follow-up, and 4-month follow-up. We recruited 102 in-patients (men: 51%) with NSCLC who underwent surgery aimed at removing a lung tumor. Self-report data were collected with QLQ-LC13 and a scale for self-efficacy for managing illness.
Mixed-models analysis indicated that trajectories of physical quality of life (symptoms of lung cancer) as well as self-efficacy were unfavorable among women with family cancer history.
Among NSCLC patients, gender and family cancer history may be considered basic screening criteria for identifying groups of patients at risk for poorer physical QOL (higher level of physical symptoms related to lung cancer) and lower incline of self-efficacy after cancer surgery.
我们调查了非小细胞肺癌（NSCLC）患者中与肺癌相关的身体症状轨迹（生活质量[QOL]的一个方面）和自我效能的决定因素。据推测，性别和一级亲属的家族癌症史会对QOL-肺癌特异性症状和自我效能产生协同作用。有家族癌症史的女性预计有调整较差的风险。
采用定量纵向设计。参与者在术后3-4天、1个月随访和4个月随访时提供了他们的回答。我们招募了102名接受旨在切除肺部肿瘤手术的NSCLC住院患者（男性：51%）。通过QLQ-LC13和疾病管理自我效能量表收集自我报告数据。
混合模型分析表明，有家族癌症史的女性在身体生活质量（肺癌症状）以及自我效能方面的轨迹不利。
在NSCLC患者中，性别和家族癌症史可被视为识别术后身体QOL较差（与肺癌相关的身体症状水平较高）和自我效能下降风险较高患者群体的基本筛查标准。
