毛细支气管炎住院儿童中呼吸道合胞病毒A、B亚型的临床特征
Clinical Profiles of Respiratory Syncytial Virus Subtypes A AND B Among Children Hospitalized with Bronchiolitis.
作者信息
Laham Federico R, Mansbach Jonathan M, Piedra Pedro A, Hasegawa Kohei, Sullivan Ashley F, Espinola Janice A, Camargo Carlos A
机构信息
From the *Department of Pediatric Infectious Diseases, Arnold Palmer Hospital for Children, Orlando, Florida; †Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts; ‡Departments of Molecular Virology and Microbiology and Pediatrics, Baylor College of Medicine, Houston, Texas; and §Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
出版信息
Pediatr Infect Dis J. 2017 Aug;36(8):808-810. doi: 10.1097/INF.0000000000001596.
Abstract
In this analysis of a prospective, multicenter study of children hospitalized with bronchiolitis, 925 had respiratory syncytial virus (RSV)-A and 649 had RSV-B. Overall, bronchiolitis severity did not differ by RSV subtype. However, among children with RSV-only bronchiolitis, those children with RSV-A had higher risk of intensive care treatment (odds ratio, 1.31; 95% confidence interval, 1.00-1.71; P = 0.048) when compared with those having RSV-B.
摘要
在这项对因细支气管炎住院儿童的前瞻性多中心研究分析中，925例感染呼吸道合胞病毒A（RSV-A），649例感染呼吸道合胞病毒B（RSV-B）。总体而言，细支气管炎的严重程度不因RSV亚型而异。然而，在仅感染RSV的细支气管炎患儿中，与感染RSV-B的患儿相比，感染RSV-A的患儿接受重症监护治疗的风险更高（比值比，1.31；95%置信区间，1.00 - 1.71；P = 0.048）。
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