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日本脑炎患者血清及脑脊液中的免疫球蛋白M、A和G

Serum and cerebrospinal fluid immunoglobulins M, A, and G in Japanese encephalitis.

作者信息

Han X Y, Ren Q W, Xu Z Y, Tsai T F

机构信息

Department of Epidemiology, Shanghai Medical University, China.

出版信息

J Clin Microbiol. 1988 May;26(5):976-8. doi: 10.1128/jcm.26.5.976-978.1988.

Abstract

A comparison was made of virus-specific immunoglobulin M (IgM), IgA, and IgG detected by capture or indirect enzyme immunoassay in serum and cerebrospinal fluid of patients with Japanese encephalitis. The IgM capture enzyme immunoassay was more sensitive than assays for other isotypes of viral antibody; IgM was detected in 75% of specimens collected less than or equal to 4 days after the onset of illness. Specific IgA was detected in both serum and cerebrospinal fluid; however, IgA levels were significantly lower than IgM levels.

摘要

对通过捕获或间接酶免疫测定法检测的日本脑炎患者血清和脑脊液中的病毒特异性免疫球蛋白M(IgM)、IgA和IgG进行了比较。IgM捕获酶免疫测定法比其他病毒抗体同型的测定法更敏感;在发病后4天及以内采集的标本中,75%检测到了IgM。血清和脑脊液中均检测到特异性IgA;然而,IgA水平明显低于IgM水平。

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Fatal outcome in Japanese encephalitis.日本脑炎的致死结局
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