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CD163, a Hemoglobin/Haptoglobin Scavenger Receptor, After Intracerebral Hemorrhage: Functions in Microglia/Macrophages Versus Neurons.

作者信息

Garton Thomas, Keep Richard F, Hua Ya, Xi Guohua

机构信息

Department of Neurosurgery, University of Michigan, R5018 Biomedical Science Research Building, 109 Zina Pitcher Place, Ann Arbor, MI, USA.

出版信息

Transl Stroke Res. 2017 Dec;8(6):612-616. doi: 10.1007/s12975-017-0535-5. Epub 2017 Apr 6.

DOI:10.1007/s12975-017-0535-5
PMID:28386733
Abstract
摘要

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Brain iron overload following intracranial haemorrhage.脑出血后的脑铁过载。
Stroke Vasc Neurol. 2016 Dec 19;1(4):172-184. doi: 10.1136/svn-2016-000042. eCollection 2016 Dec.
2
Neuronal Death After Hemorrhagic Stroke In Vitro and In Vivo Shares Features of Ferroptosis and Necroptosis.出血性中风后体外和体内的神经元死亡具有铁死亡和坏死性凋亡的特征。
Stroke. 2017 Apr;48(4):1033-1043. doi: 10.1161/STROKEAHA.116.015609. Epub 2017 Mar 1.
3
Soluble ectodomain CD163 and extracellular vesicle-associated CD163 are two differently regulated forms of 'soluble CD163' in plasma.
脑出血后铁死亡相关的病理损伤机制及治疗策略
Front Neurol. 2025 May 1;16:1508718. doi: 10.3389/fneur.2025.1508718. eCollection 2025.
4
The involvement of mitochondria in erythrocyte pathology and diseases: from mechanisms to therapeutic strategies.线粒体在红细胞病理学及疾病中的作用：从机制到治疗策略
Clin Exp Med. 2025 May 9;25(1):144. doi: 10.1007/s10238-024-01555-1.
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Involvement of virus infections and antiviral agents in schizophrenia.病毒感染及抗病毒药物与精神分裂症的关联。
Psychol Med. 2025 Mar 10;55:e73. doi: 10.1017/S0033291725000467.
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TRIOL attenuates intracerebral hemorrhage injury by bidirectionally modulating microglia- and neuron-mediated hematoma clearance.TRIOL通过双向调节小胶质细胞和神经元介导的血肿清除来减轻脑出血损伤。
Redox Biol. 2025 Mar;80:103487. doi: 10.1016/j.redox.2024.103487. Epub 2024 Dec 31.
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Multimodal and serial MRI monitors brain peri-hematomal injury and repair mechanisms after experimental intracerebral hemorrhage.多模态和序列磁共振成像监测实验性脑出血后脑血肿周围损伤及修复机制。
J Cereb Blood Flow Metab. 2025 Jan;45(1):140-152. doi: 10.1177/0271678X241270198. Epub 2024 Aug 7.
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Recent advances in potential therapeutic targets of ferroptosis‑associated pathways for the treatment of stroke (Review).铁死亡相关通路在脑卒中治疗中潜在治疗靶点的研究进展（综述）。
Mol Med Rep. 2024 Jul;30(1). doi: 10.3892/mmr.2024.13252. Epub 2024 May 24.
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Transcriptomic analysis reveals sex-specific patterns in the hippocampus in Alzheimer's disease.转录组分析揭示了阿尔茨海默病中海马的性别特异性模式。
Front Endocrinol (Lausanne). 2024 Apr 16;15:1345498. doi: 10.3389/fendo.2024.1345498. eCollection 2024.
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J Cereb Blood Flow Metab. 2024 Jun;44(6):841-856. doi: 10.1177/0271678X241237070. Epub 2024 Feb 28.
可溶性细胞外结构域 CD163 和细胞外囊泡相关 CD163 是血浆中两种不同调节形式的“可溶性 CD163”。
Sci Rep. 2017 Jan 13;7:40286. doi: 10.1038/srep40286.
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Early Erythrolysis in the Hematoma After Experimental Intracerebral Hemorrhage.实验性脑出血后血肿内的早期红细胞溶解
Transl Stroke Res. 2017 Apr;8(2):174-182. doi: 10.1007/s12975-016-0505-3. Epub 2016 Oct 25.
5
CD163 promotes hematoma absorption and improves neurological functions in patients with intracerebral hemorrhage.CD163可促进脑出血患者血肿吸收并改善神经功能。
Neural Regen Res. 2016 Jul;11(7):1122-7. doi: 10.4103/1673-5374.187047.
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Haptoglobin increases the vulnerability of CD163-expressing neurons to hemoglobin.触珠蛋白增加了表达CD163的神经元对血红蛋白的易损性。
J Neurochem. 2016 Nov;139(4):586-595. doi: 10.1111/jnc.13720. Epub 2016 Jul 22.
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Intraventricular Hemorrhage: the Role of Blood Components in Secondary Injury and Hydrocephalus.脑室内出血：血液成分在继发性损伤和脑积水形成中的作用
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Transl Stroke Res. 2016 Dec;7(6):478-487. doi: 10.1007/s12975-016-0472-8. Epub 2016 May 21.
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Hematoma Changes During Clot Resolution After Experimental Intracerebral Hemorrhage.实验性脑出血后血凝块溶解过程中的血肿变化
Stroke. 2016 Jun;47(6):1626-31. doi: 10.1161/STROKEAHA.116.013146. Epub 2016 Apr 28.
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Alternatively activated brain-infiltrating macrophages facilitate recovery from collagenase-induced intracerebral hemorrhage.交替活化的脑浸润巨噬细胞促进胶原酶诱导的脑出血后的恢复。
Mol Brain. 2016 Apr 19;9:42. doi: 10.1186/s13041-016-0225-3.