2016年德国首例由K2血清型ST2398高毒力菌株引起的侵袭性肝脓肿综合征合并眼内炎报告。
First report of invasive liver abscess syndrome with endophthalmitis caused by a K2 serotype ST2398 hypervirulent in Germany, 2016.
作者信息
Pichler C, Büchsel M, Rossen J W, Vavra M, Reuter S, Kern W V, Thimme R, Mischnik A
机构信息
Department of Medicine II, Medical Center - University of Freiburg, Faculty of Medicine, Freiburg, Germany.
Institute for Medical Microbiology and Hygiene, Medical Center - University of Freiburg, Faculty of Medicine, Freiburg, Germany.
出版信息
New Microbes New Infect. 2017 Mar 3;17:77-80. doi: 10.1016/j.nmni.2017.02.006. eCollection 2017 May.
We report a case of severe infection with liver abscess and endophthalmitis caused by a hypervirulent strain in an immunocompetent German male patient without travel history to Asia. Phenotypic and molecular characterization showed high similarity to the reference genome NTUH-K2044 isolated in Asia. The isolate was assigned as ST2398 (clonal complex 66). The findings underline global spread of hypervirulent strains to Europe.
我们报告了一例由高毒力菌株引起的严重感染病例，该病例发生在一名没有前往亚洲旅行史的免疫功能正常的德国男性患者身上，感染导致肝脓肿和眼内炎。表型和分子特征分析显示，该菌株与在亚洲分离出的参考基因组NTUH-K2044高度相似。该分离株被归类为ST2398（克隆复合体66）。这些发现强调了高毒力菌株在全球范围内向欧洲的传播。
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