Vanarase Mithila, Gautam Ram Krishan, Arora Pooja, Bajaj Sonali, Meena Neha, Khurana Ananta
a Department of Dermatology , Venereology and Leprosy, Dr Ram Manohar Lohia Hospital , New Delhi , India.
J Cosmet Laser Ther. 2017 Oct;19(5):259-265. doi: 10.1080/14764172.2017.1314506. Epub 2017 Apr 10.
Q-switched lasers are conventionally used for the treatment of black tattoo. However, they require multiple sittings, and the response may be slow due to competing epidermal pigment in dark skin.
To compare the efficacy of Q-switched Nd:YAG laser alone with its combination with ultrapulse CO for the removal of black tattoo.
Sixty patients with black tattoo were randomized into two groups viz., group A and group B. Group A was treated with QS Nd:YAG laser (1064 nm) alone, and group B received combination of ablative ultrapulse CO followed by fixed-dose QS Nd:YAG laser (1064 nm), at 6-week interval for a maximum of 6 sittings. After each sitting, 3 independent physicians noted percentage of improvement that was evaluated using visual analogue scale (VAS) and grading system for tattoo ink lightening (TIL).
Combination laser (group B) showed statistically significant improvement in mean VAS score in the last 2 noted visits as compared to 1st session (p < 0.007, p < 0.001) and TIL mean score in last three noted visits as compared to 1st session (p < 0.008, p < 0.020, and p < 0.004). There was no statistically significant difference in the side effect profile of both the groups.
For refractory professional tattoos, combination of ultrapulse CO laser and QS Nd:YAG laser is superior to QS Nd:YAG laser alone.
调Q激光传统上用于治疗黑色纹身。然而，它们需要多次治疗，并且由于深色皮肤中存在竞争性表皮色素，反应可能较慢。
比较单独使用调Q Nd:YAG激光及其与超脉冲CO₂激光联合使用去除黑色纹身的疗效。
60例黑色纹身患者随机分为两组，即A组和B组。A组仅接受调Q Nd:YAG激光（1064nm）治疗，B组先接受超脉冲CO₂激光消融，然后每隔6周接受固定剂量的调Q Nd:YAG激光（1064nm）治疗，最多6次。每次治疗后，3名独立的医生记录改善百分比，使用视觉模拟量表（VAS）和纹身墨水淡化分级系统（TIL）进行评估。
与第一次治疗相比，联合激光组（B组）在最后两次记录的就诊中平均VAS评分有统计学显著改善（p<0.007，p<0.001），在最后三次记录的就诊中TIL平均评分与第一次治疗相比有统计学显著改善（p<0.008，p<0.020，p<0.004）。两组的副作用情况无统计学显著差异。
对于难治性职业纹身，超脉冲CO₂激光和调Q Nd:YAG激光联合使用优于单独使用调Q Nd:YAG激光。
