Calogiuri Gianfranco, Di Leo Elisabetta, Butani Lavjay, Pizzimenti Stefano, Incorvaia Cristoforo, Macchia Luigi, Nettis Eustachio
Pneumology and Allergy Department, Hospital Sacro Cuore, Gallipoli, Lecce, Italy.
Section of Allergy and Clinical Immunology, Unit of Internal Medicine-"F. Miulli" Hospital, Acquaviva delle Fonti, Bari, Italy.
Clin Mol Allergy. 2017 Apr 10;15:8. doi: 10.1186/s12948-017-0063-6. eCollection 2017.
Hypersensitivity to para-phenylenediamine (PPD) and related compounds induced by temporary black henna tattoos has become a serious health problem worldwide. Different patterns of sensitization with various clinical aspects are described in literature due to PPD associated to henna tattoo and these manifestations are likely correlated with the immunological and dermatological pathomechanisms involved. Henna is the Persian name of the plant Fam. . It is a woody shrub that grow in regions of North Africa, South Asia, India and Sri Lanka. Nowadays it is rather frequent to see temporary "tattoos" performed with henna. To make tattoos darker and long-lasting PPD has been associated to henna in tattoo drawings mixtures, so obtaining "". In these years there has been a rise of contact sensitization to PPD and in medical literature an increased number of cases have been reported on temporary henna tattoo application. Here we review the various clinical patterns related to PPD and henna tattoo, to investigate the possible link between clinic-morphological pictures and the immunological response to PPD and henna. The literature underlines that different clinical manifestations are related to black henna containing PPD, and its derivative products may cause delayed-type as well as immediate-type reactions. Further studies are needed to investigate the relationship between clinical and morphological aspects of PPD contact dermatitis and the T cell subsets predominance.
由临时黑指甲花纹身引起的对对苯二胺（PPD）及相关化合物的超敏反应已成为全球范围内一个严重的健康问题。由于与指甲花纹身相关的PPD，文献中描述了具有各种临床特征的不同致敏模式，这些表现可能与所涉及的免疫和皮肤病发病机制相关。指甲花是植物……科的波斯名称。它是一种生长在北非、南亚、印度和斯里兰卡地区的木本灌木。如今，用指甲花进行临时“纹身”相当常见。为了使纹身颜色更深且持久，在纹身绘图混合物中PPD已与指甲花混合使用，从而得到“”。近年来，对PPD的接触致敏有所增加，医学文献中报道的临时指甲花纹身应用病例数量也有所增加。在此，我们回顾与PPD和指甲花纹身相关的各种临床模式，以研究临床形态学表现与对PPD和指甲花的免疫反应之间的可能联系。文献强调，不同的临床表现与含PPD的黑指甲花有关，其衍生产品可能引起迟发型以及速发型反应。需要进一步研究来探讨PPD接触性皮炎的临床和形态学方面与T细胞亚群优势之间的关系。
