手术缝合诱导的黑素细胞痣。一种新型的发疹性黑素细胞痣？
Surgical suturing-induced melanocytic nevi. A new type of eruptive melanocytic nevi?
作者信息
Katoulis Alexander C, Sgouros Dimitrios, Argenziano Giuseppe, Rallis Efstathios, Panayiotides Ioannis, Rigopoulos Dimitrios
机构信息
2nd Department of Dermatology and Venereology, National and Kapodistrian University of Athens, Medical School, "Attikon" University General Hospital, 1 Rimini str, 12462, Chaidari, Athens, Greece.
Dermatology Unit, 2nd University of Naples, 43 Antonio Vivaldi str, 81100, Caserta CE, Naples, Italy.
出版信息
J Dermatol Case Rep. 2016 Nov 30;10(3):49-52. doi: 10.3315/jdcr.2016.1233.
BACKGROUND
Nevogenesis is a complex process involving several pathogenetic mechanisms, including genetic factors, hormonal influences and UV-radiation. Trauma has been described as a triggering factor for an alternative pathway of nevogenesis. Eruptive melanocytic nevi (EMN), related either to immunosuppression or to blistering disorders, represent a special type of nevi probably induced by the disruption of the dermo-epidermal junction and consequent proliferation of quiescent pigment cells during re-epithelization.
MAIN OBSERVATIONS
We report two patients with three melanocytic nevi that developed de novo along the direction of surgical suturing, following surgical operation for other reason. The lesions exhibited special dermoscopic characteristics and histology revealed features of acquired melanocytic nevi.
CONCLUSIONS
Such cases may represent a new type of eruptive nevus, the surgical suturing-induced nevus, which should be included in the differential diagnosis of new pigmentation developing within a scar.
背景
痣形成是一个复杂的过程，涉及多种致病机制，包括遗传因素、激素影响和紫外线辐射。创伤已被描述为痣形成替代途径的触发因素。与免疫抑制或水疱性疾病相关的发疹性黑素细胞痣（EMN）是一种特殊类型的痣，可能是由于真皮-表皮交界处的破坏以及静止色素细胞在再上皮化过程中随之增殖所致。
主要观察结果
我们报告了两名患者，他们在因其他原因进行手术后，沿着手术缝线方向新发了三颗黑素细胞痣。这些病变表现出特殊的皮肤镜特征，组织学显示为后天性黑素细胞痣的特征。
结论
此类病例可能代表一种新型的发疹性痣，即手术缝线诱导痣，应纳入瘢痕内新出现色素沉着的鉴别诊断。
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