Grundy Anne, Poirier Abbey E, Khandwala Farah, McFadden Alison, Friedenreich Christine M, Brenner Darren R
Department of Cancer Epidemiology and Prevention Research (Grundy, Poirier, Khandwala, McFadden, Friedenreich, Brenner), CancerControl Alberta, Alberta Health Services; Department of Oncology, Cumming School of Medicine (Friedenreich, Brenner), University of Calgary; Department of Community Health Sciences (Friedenreich, Brenner), Cumming School of Medicine, University of Calgary, Calgary, Alta.
CMAJ Open. 2017 Jan 4;5(1):E7-E13. doi: 10.9778/cmajo.20160043. eCollection 2017 Jan-Mar.
Insufficient fibre consumption has been associated with a increased risk of colorectal cancer. The purpose of this study was to estimate the proportion and absolute number of cancers in Alberta that could be attributed to insufficient fibre consumption in 2012.
The number and proportion of colorectal cancers in Alberta attributable to insufficient fibre consumption were estimated using the population attributable risk. Relative risks were obtained from the World Cancer Research Fund's 2011 Continuous Update Project on colorectal cancer, and the prevalence of insufficient fibre consumption (< 23 g/d) was estimated using dietary data from Alberta's Tomorrow Project. Age- and sex-specific colorectal cancer incidence data for 2012 were obtained from the Alberta Cancer Registry.
Between 66% and 67% of men and between 73% and 78% of women reported a diet with insufficient fibre consumption. Population attributable risk estimates for colorectal cancer were marginally higher in men, ranging from 6.3% to 6.8% across age groups, whereas in women they ranged from 5.0% to 5.5%. Overall, 6.0% of colorectal cancers or 0.7% of all cancers in Alberta in 2012 were estimated to be attributable to insufficient fibre consumption.
Insufficient fibre consumption accounted for 6.0% of colorectal cancers in Alberta in 2012. Increasing fibre consumption in Alberta has the potential to reduce to the future burden of colorectal cancer in the province.
膳食纤维摄入不足与结直肠癌风险增加有关。本研究的目的是估计2012年艾伯塔省可归因于膳食纤维摄入不足的癌症比例和绝对数量。
使用人群归因风险来估计艾伯塔省可归因于膳食纤维摄入不足的结直肠癌数量和比例。相对风险来自世界癌症研究基金会2011年关于结直肠癌的持续更新项目，膳食纤维摄入不足（<23克/天）的患病率使用艾伯塔省明日项目的饮食数据进行估计。2012年特定年龄和性别的结直肠癌发病率数据来自艾伯塔癌症登记处。
66%至67%的男性和73%至78%的女性报告膳食纤维摄入不足。男性结直肠癌的人群归因风险估计略高，各年龄组范围为6.3%至6.8%，而女性为5.0%至5.5%。总体而言，估计2012年艾伯塔省6.0%的结直肠癌或所有癌症的0.7%可归因于膳食纤维摄入不足。
2012年艾伯塔省6.0%的结直肠癌可归因于膳食纤维摄入不足。增加艾伯塔省的膳食纤维摄入量有可能减轻该省未来结直肠癌的负担。
