Bonati Lauren Meshkov, Epstein Gorana Kuka, Strugar Tamara Lazic
J Drugs Dermatol. 2017 Apr 1;16(4):308-313.
INTRODUCTION: Microneedling procedures are growing in popularity for a wide variety of skin conditions. This paper comprehensively reviews the medical literature regarding skin needling efficacy and safety in all skin types and in multiple dermatologic conditions.
METHODS: A PubMed literature search was conducted in all languages without restriction and bibliographies of relevant articles reviewed. Search terms included: "microneedling," "percutaneous collagen induction," "needling," "skin needling," and "dermaroller."
RESULTS: Microneedling is most commonly used for acne scars and cosmetic rejuvenation, however, treatment benefit has also been seen in varicella scars, burn scars, keloids, acne, alopecia, and periorbital melanosis, and has improved flap and graft survival, and enhanced transdermal delivery of topical products. Side effects were mild and self-limited, with few reports of post-inflammatory hyperpigmentation, and isolated reports of tram tracking, facial allergic granuloma, and systemic hypersensitivity.
DISCUSS: Microneedling represents a safe, cost-effective, and efficacious treatment option for a variety of dermatologic conditions in all skin types. More double-blinded, randomized, controlled trials are required to make more definitive conclusions.
J Drugs Dermatol. 2017;16(4):308-314.
.微针疗法因能治疗多种皮肤问题而越来越受欢迎。本文全面回顾了关于所有皮肤类型及多种皮肤病中皮肤微针疗法的疗效和安全性的医学文献。
对PubMed数据库进行无语言限制的文献检索，并查阅相关文章的参考文献。检索词包括：“微针疗法”“经皮胶原诱导”“针刺”“皮肤微针疗法”和“微针滚轮”。
微针疗法最常用于治疗痤疮瘢痕和美容嫩肤，不过，在水痘瘢痕、烧伤瘢痕、瘢痕疙瘩、痤疮、脱发及眶周色素沉着症的治疗中也有疗效，并且还改善了皮瓣和移植物的存活情况，增强了局部用药的透皮递送。副作用轻微且具有自限性，炎症后色素沉着的报告较少，还有关于轨道状痕迹、面部过敏性肉芽肿及全身超敏反应的个别报告。
微针疗法是一种安全、经济有效且能治疗所有皮肤类型的多种皮肤病的治疗方法。需要更多双盲、随机、对照试验以得出更明确的结论。
《皮肤药物学杂志》2017年；16(4)：308 - 314。
