Von Dalwig-Nolda Dirk Freiherr, Ablon Glynis
Dr. Freiherr von Dalwig-Nolda is with the DermaVen Center in Bad Salzuflen, Germany.
Dr. Ablon is with the University of California, Los Angeles in Los Angeles, California and the Ablon Skin Institute & Research Center in Manhattan Beach, California.
J Clin Aesthet Dermatol. 2020 Aug;13(8):17-22. Epub 2020 Aug 1.
To assess the effectiveness of the amiea med (amiea med, MT.DERM GmbH, Berlin, Germany) automated microneedling device in reducing facial atrophic acne scars. : Open label, single center. Healthy males and females, aged 18 to 65 years, with signs of facial atrophic acne scarring were selected. After consenting and satisfying inclusion criteria, each subject underwent four microneedling sessions 30 days apart. Subjects were assessed at baseline and three months after the last treatment. Acne scars were classified according to Jacob classification. Physician assessment of acne scarring severity was carried out using the Goodman and Baron grading scale. Subjects graded their redness, pain and discomfort on the evening of the treatment and up to seven days posttreatment using a subject diary. Three months after the last treatment, facial acne scars had improved by 0.91 of a grade [CI. 0.78-1.05] according to Goodman and Baron Grading Scale (<0.001). Improvement in acne scarring was not restricted to severity of grade,with no difference seen in Fitzpatrick skin types. According to Jacob classification, rolling scars showed the greatest improvement, with a mean improvement of 1.06 of a grade at the final assessment (<0.001). This study demonstrates that four microneedling treatments of facial skin, spaced four weeks apart, significantly improves the appearance of facial acne scarring. The treatment is well tolerated with minimal pain, discomfort, and downtime. Side effects appear minor and easily managed compared to other more aggressive technologies. German Register for Clinical studies (DRKS) No [DRKS00013187].
评估德国柏林MT.DERM GmbH公司的amiea med自动微针设备在减轻面部萎缩性痤疮瘢痕方面的有效性。：开放标签、单中心研究。选取年龄在18至65岁之间、有面部萎缩性痤疮瘢痕迹象的健康男性和女性。在获得同意并满足纳入标准后，每位受试者每隔30天接受4次微针治疗。在基线和最后一次治疗后三个月对受试者进行评估。痤疮瘢痕根据雅各布分类法进行分类。使用古德曼和巴伦分级量表对痤疮瘢痕严重程度进行医生评估。受试者在治疗当晚及治疗后长达7天使用受试者日记对自身的发红、疼痛和不适进行评分。根据古德曼和巴伦分级量表，最后一次治疗后三个月，面部痤疮瘢痕改善了0.91级[置信区间0.78 - 1.05]（<0.001）。痤疮瘢痕的改善不限于等级严重程度，在菲茨帕特里克皮肤类型方面未见差异。根据雅各布分类法，滚轮状瘢痕改善最为显著，最终评估时平均改善了1.06级（<0.001）。本研究表明，对面部皮肤进行4次微针治疗，每次间隔4周，可显著改善面部痤疮瘢痕外观。该治疗耐受性良好，疼痛、不适和停工期最小。与其他更激进的技术相比，副作用较小且易于处理。德国临床研究注册编号[DRKS00013187]
