皮质类固醇用于预防急性肾盂肾炎患儿的肾瘢痕形成。
Corticosteroids for renal scar prevention in children with acute pyelonephritis.
作者信息
Sakulchit Teeranai, Goldman Ran D
出版信息
Can Fam Physician. 2017 Apr;63(4):286-287.
Abstract
Acute pyelonephritis in children is of great concern and I usually refer these patients to a pediatrician or send them to the emergency department owing to the risk of renal scarring. Are steroids an acceptable treatment to reduce risk of scarring? Several agents have been studied in an effort to prevent renal scar formation following acute pyelonephritis in children. Use of corticosteroids, in conjunction with standard therapy for acute pyelonephritis, shows promising findings. However, evidence is very limited and steroids should not be offered on a regular basis as part of treatment.
摘要
儿童急性肾盂肾炎备受关注，由于存在肾瘢痕形成的风险，我通常会将这些患者转诊给儿科医生或送往急诊科。类固醇是否是降低瘢痕形成风险的可接受治疗方法？为了预防儿童急性肾盂肾炎后的肾瘢痕形成，已经对几种药物进行了研究。在急性肾盂肾炎的标准治疗基础上联合使用皮质类固醇显示出有前景的结果。然而，证据非常有限，类固醇不应作为常规治疗的一部分。
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