Cardoso Juliana Andrade, Dos Santos Junior André Avelino, Nunes Maria Lucia Tiellet, de Figueiredo Maria Antonia Zancanaro, Cherubini Karen, Salum Fernanda Gonçalves
Oral Medicine Division, São Lucas Hospital, Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, RS, Brazil.
Cellular and Molecular Biology, Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, RS, Brazil.
Int J Dent. 2017;2017:5269856. doi: 10.1155/2017/5269856. Epub 2017 Mar 19.
. The aim of this study was to evaluate stress, anxiety, and salivary alpha-amylase (SAA) activity in patients with recurrent aphthous stomatitis (RAS). The impact of this disease on the life quality was also evaluated. . Twenty-two patients with RAS and controls, matched by sex and age, were selected. Stress and anxiety were assessed using Lipp's Inventory of Stress Symptoms and Beck Anxiety Inventory. Life quality was assessed through the World Health Organization Quality of Life-bref (WHOQOL-BREF) and the Oral Health Impact Profile-14 (OHIP-14). Saliva samples were collected in the morning and afternoon and the SAA activity was analyzed by enzymatic kinetic method. . No significant difference was observed between the groups regarding the SAA activity ( = 0.306). Patients with RAS had higher scores of anxiety ( = 0.016). The scores of WHOQOL-BREF were significantly lower in patients with RAS. The values obtained through OHIP-14 were significantly higher in these patients ( = 0.002). . RAS negatively affects the life quality. Patients with the disease have higher levels of anxiety, suggesting its association with the etiopathogenesis of RAS.
本研究旨在评估复发性阿弗他口炎（RAS）患者的应激、焦虑及唾液α淀粉酶（SAA）活性。同时评估了该疾病对生活质量的影响。
选取了22例RAS患者及年龄、性别匹配的对照组。采用利普应激症状量表和贝克焦虑量表评估应激和焦虑。通过世界卫生组织生活质量简表（WHOQOL - BREF）和口腔健康影响程度量表 - 14（OHIP - 14）评估生活质量。于上午和下午采集唾液样本，采用酶动力学方法分析SAA活性。
两组间SAA活性无显著差异（P = 0.306）。RAS患者焦虑得分更高（P = 0.016）。RAS患者的WHOQOL - BREF得分显著更低。通过OHIP - 14获得的值在这些患者中显著更高（P = 0.002）。
RAS对生活质量有负面影响。该疾病患者焦虑水平更高，提示其与RAS的病因发病机制有关。
