Council for Agricultural Research and Economics (CREA), Research Center for Food and Nutrition, Via Ardeatina 546, 00178 Rome, Italy.
Diabetes Unit, San Camilo-Forlanini Hospital, Rome, Italy.
Oxid Med Cell Longev. 2017;2017:1672567. doi: 10.1155/2017/1672567. Epub 2017 Mar 20.
The main objective of this research was to determine whether a commercial orange juice rich in anthocyanins could have an effect on body weight and on clinical parameters related to obesity including antioxidant status, lipid profile, and metabolic and inflammatory biomarkers. 11 women with an average BMI of 34.4 ± 4.8 kg/m were enrolled in a pilot study. Over a period of 12 weeks they received 500 mL daily dose into two doses (250 mL) of commercial red orange juice (COJ). The biochemical parameters were measured at baseline and at the end of the study (12 weeks). One month later upon free diet, a follow-up was performed measuring the same variables. The daily consumption of 500 mL of COJ had no significant effects on body weight, while there was a decrease in total cholesterol and LDL cholesterol. The grade of obesity implies different changes in inflammation biomarkers. In obese women, our data do not seem to support evidence that commercial red orange juice consumption acts as functional food preventing obesity and metabolic disorders such as insulin resistance and/or inflammatory status.
本研究的主要目的是确定富含花色苷的商业橙汁是否对体重以及与肥胖相关的临床参数（包括抗氧化状态、血脂谱、代谢和炎症生物标志物）有影响。11 名平均 BMI 为 34.4±4.8kg/m²的女性参与了一项试点研究。在 12 周的时间里，她们每天接受两次（每次 250 毫升）500 毫升的商业红橙汁（COJ）剂量。在基线和研究结束时（12 周）测量生化参数。一个月后，在自由饮食的情况下，进行了随访，测量了相同的变量。每天饮用 500 毫升 COJ 对体重没有显著影响，而总胆固醇和 LDL 胆固醇有所下降。肥胖程度的不同会导致炎症生物标志物的变化。在肥胖女性中，我们的数据似乎不支持商业红橙汁消费作为功能性食品预防肥胖和代谢紊乱（如胰岛素抵抗和/或炎症状态）的证据。
