当癌症需要非必要的东西时。
When cancer needs what's non-essential.
机构信息
Koch Institute for Integrative Cancer Research and the Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA.
出版信息
Nat Cell Biol. 2017 May;19(5):418-420. doi: 10.1038/ncb3523. Epub 2017 Apr 19.
DOI:10.1038/ncb3523
PMID:28422952
Abstract
The non-essential amino acids serine and glycine are critical for proliferative metabolism. A study in Nature now finds that dietary serine and glycine deprivation inhibits growth of some tumours. Whether this dietary intervention is effective depends on both the oncogenic context and tumour tissue of origin.
摘要
非必需氨基酸丝氨酸和甘氨酸对增殖代谢至关重要。《自然》杂志的一项新研究发现，饮食中丝氨酸和甘氨酸的缺乏会抑制某些肿瘤的生长。这种饮食干预是否有效取决于致癌环境和肿瘤组织的来源。
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