Department of Radiology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA, 01655, USA.
J Nucl Cardiol. 2020 Feb;27(1):80-95. doi: 10.1007/s12350-017-0890-3. Epub 2017 Apr 21.
Respiratory motion can deteriorate image fidelity in cardiac perfusion SPECT. We determined the extent of respiratory motion, assessed its impact on image fidelity, and investigated the existence of gender differences, thereby examining the influence of respiratory motion in a large population of patients.
One thousand one hundred and three SPECT/CT patients underwent visual tracking of markers on their anterior surface during stress acquisition to track respiratory motion. The extent of motion was estimated by registration. Visual indicators of changes in cardiac slices with motion correction, and the correlation between the extent of motion with changes in segmental-counts were assessed.
Respiratory motion in the head-to-feet direction was the largest component of motion, varying between 1.1 and 37.4 mm, and was statistically significantly higher (p = 0.002) for males than females. In 33.0% of the patients, motion estimates were larger than 10 mm. Patients progressively show more distinct visual changes with an increase in the extent of motion. The increase in segmental-count differences in the anterior, antero-lateral, and inferior segments correlated with the extent of motion.
Respiratory motion correction diminished the artefactual reduction in anterior and inferior wall counts associated with respiratory motion. The extent of improvement was strongly related to the magnitude of motion.
呼吸运动会降低心脏灌注 SPECT 的图像逼真度。我们确定了呼吸运动的程度，评估了它对图像逼真度的影响，并研究了性别差异的存在，从而在大量患者中检查了呼吸运动的影响。
1103 名 SPECT/CT 患者在应激采集期间接受其前表面标记物的视觉跟踪，以跟踪呼吸运动。通过配准来估计运动的程度。评估了带有运动校正的心脏切片中变化的视觉指标，以及运动程度与节段计数变化之间的相关性。
头到脚方向的呼吸运动是运动的最大组成部分，变化范围为 1.1 至 37.4 毫米，男性明显高于女性（p=0.002）。在 33.0%的患者中，运动估计值大于 10 毫米。随着运动程度的增加，患者逐渐表现出更明显的视觉变化。前、前外侧和下节段的节段计数差异增加与运动程度相关。
呼吸运动校正减少了与呼吸运动相关的前壁和下壁计数的人为减少。改善的程度与运动幅度密切相关。
