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血液系统恶性肿瘤的免疫治疗:过去、现在与未来。

Immunotherapy in hematologic malignancies: past, present, and future.

作者信息

Im Annie, Pavletic Steven Z

机构信息

University of Pittsburgh Cancer Institute, 5150 Centre Ave, Suite 554, Pittsburgh, PA, 15213, USA.

National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

出版信息

J Hematol Oncol. 2017 Apr 24;10(1):94. doi: 10.1186/s13045-017-0453-8.

Abstract

The field of immunotherapy in cancer treatments has been accelerating over recent years and has entered the forefront as a leading area of ongoing research and promising therapies that have changed the treatment landscape for a variety of solid malignancies. Prior to its designation as the Science Breakthrough of the Year in 2013, cancer immunotherapy was active in the treatment of hematologic malignancies. This review provides a broad overview of the past, present, and potential future of immunotherapy in hematologic malignancies.

摘要

近年来,癌症治疗中的免疫疗法领域发展迅速,已成为前沿领域,作为一个正在进行研究且有前景的治疗领域,改变了多种实体恶性肿瘤的治疗格局。在2013年被指定为年度科学突破之前,癌症免疫疗法就已活跃于血液系统恶性肿瘤的治疗中。本文综述了免疫疗法在血液系统恶性肿瘤治疗中的过去、现状及潜在的未来发展情况。

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