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经尿道前列腺单极切除术期间耻骨上膀胱造瘘术与非耻骨上膀胱造瘘术的倾向评分匹配分析

Suprapubic cystostomy versus nonsuprapubic cystostomy during monopolar transurethral resection of prostate: a propensity score-matched analysis.

作者信息

Guo Run-Qi, Meng Yi-Sen, Yu Wei, Zhang Kai, Xu Ben, Xiao Yun-Xiang, Wu Shi-Liang, Pan Bai-Nian

机构信息

Department of Urology, Peking University First Hospital and Institute of Urology, National Research Center for Genitourinary Oncology, Beijing 100034.

出版信息

Asian J Androl. 2018 Jan-Feb;20(1):62-68. doi: 10.4103/aja.aja_6_17.

Abstract

We aim to reassess the safety of the monopolar transurethral resection of the prostate (M-TURP) without suprapubic cystostomy at our institution over the past decade. This retrospective study was conducted in patients who underwent M-TURP at Peking University First Hospital between 2003 and 2013. A total of 1680 patients who had undergone M-TURP were identified, including 539 patients in the noncystostomy group and 1141 patients in the cystostomy group. After propensity score matching, the number of patients in each group was 456. Smaller reductions in hemoglobin and hematocrit (10.9 g vs 17.6 g and 3.6% vs 4.7%, respectively) were found in the noncystostomy group. In addition, patients undergoing surgery without cystostomy had their catheters removed earlier (4.6 days vs 5.2 days), required shorter postoperative stays in the hospital (5.1 days vs 6.0 days), and were at lower risk of operative complications (5.7% vs 9.2%), especially bleeding requiring blood transfusion (2.9% vs 6.1%). Similar findings were observed in cohorts of prostates of 30-80 ml and prostates >80 ml. Furthermore, among patients with a resection weight >42.5 g or surgical time >90 min, or even propensity-matched patients based on surgical time, those with cystostomy seemed to be at a higher risk of operative complications. These results suggest that M-TURP without suprapubic cystostomy is a safe and effective method, even among patients with larger prostates, heavier estimated resection weights, and longer surgical times.

摘要

我们旨在重新评估过去十年间在我们机构进行的不做耻骨上膀胱造瘘的单极经尿道前列腺切除术(M-TURP)的安全性。这项回顾性研究针对2003年至2013年期间在北京大学第一医院接受M-TURP的患者开展。共确定了1680例接受M-TURP的患者,其中非膀胱造瘘组539例,膀胱造瘘组1141例。经过倾向评分匹配后,每组患者数量为456例。非膀胱造瘘组血红蛋白和血细胞比容的下降幅度较小(分别为10.9 g对17.6 g和3.6%对4.7%)。此外,未进行膀胱造瘘手术的患者导尿管拔除更早(4.6天对5.2天),术后住院时间更短(5.1天对6.0天),手术并发症风险更低(5.7%对9.2%),尤其是需要输血的出血情况(2.9%对6.1%)。在前列腺体积为30 - 80 ml和前列腺体积>80 ml的队列中观察到了类似的结果。此外,在切除重量>42.5 g或手术时间>90分钟的患者中,甚至在根据手术时间进行倾向评分匹配的患者中,进行膀胱造瘘的患者手术并发症风险似乎更高。这些结果表明,不做耻骨上膀胱造瘘的M-TURP是一种安全有效的方法,即使在前列腺体积较大、估计切除重量较重和手术时间较长的患者中也是如此。

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