钆喷酸葡胺及其类似物：现状与未来展望。
Ga-DOTA and analogs: Current status and future perspectives.
作者信息
Kilian Krzysztof
机构信息
Heavy Ion Laboratory, University of Warsaw, Pasteur 5a, 02093 Warsaw, Poland.
出版信息
Rep Pract Oncol Radiother. 2014 May 19;19(Suppl):S13-S21. doi: 10.1016/j.rpor.2014.04.016. eCollection 2014 May.
Abstract
The construction of the Ge/Ga generator has increased application of radiopharmaceuticals labeled with this isotope in medicine. Ga-PET is widely employed in the management of neuroendocrine tumors but favorable chemistry with tri- and tetraaza-ring molecules has opened wide range of Ga application in other fields of PET imaging. This review covers the radiopharmaceuticals labeled with gallium in molecular imaging and shows perspectives on the use of gallium-68 as a substitute for technetium-99, fluorine-18 and carbon-11 in some applications.
摘要
锗/镓发生器的构建增加了这种同位素标记的放射性药物在医学中的应用。镓-正电子发射断层扫描（Ga-PET）广泛应用于神经内分泌肿瘤的管理，但与三氮杂环和四氮杂环分子良好的化学反应性开启了镓在正电子发射断层扫描成像其他领域的广泛应用。本综述涵盖了分子成像中镓标记的放射性药物，并展示了在某些应用中使用镓-68替代锝-99、氟-18和碳-11的前景。
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