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本文引用的文献

1
Extramedullary Manifestations of Myeloid Neoplasms.髓系肿瘤的髓外表现
Am J Clin Pathol. 2015 Aug;144(2):219-39. doi: 10.1309/AJCPO58YWIBUBESX.
2
Risk factors and clinical outcomes of acute myeloid leukaemia with central nervous system involvement in adults.成人急性髓系白血病合并中枢神经系统受累的危险因素及临床结局
BMC Cancer. 2015 May 2;15:344. doi: 10.1186/s12885-015-1376-9.
3
Sacral canal myeloid sarcoma as initial manifestation of granulocytic leukemia: MRI features and differential diagnosis (with a case report).骶管髓系肉瘤作为粒细胞白血病的首发表现:MRI特征及鉴别诊断(附病例报告)
Turk Neurosurg. 2014;24(2):281-3. doi: 10.5137/1019-5149.JTN.7125-12.1.
4
Leukostasis in an Adult with AML Presenting as Multiple High Attenuation Brain Masses on CT.一名急性髓系白血病成年患者的白细胞淤滞在CT上表现为多个高密度脑肿块。
J Clin Diagn Res. 2013 Dec;7(12):3020-2. doi: 10.7860/JCDR/2013/6638.3893. Epub 2013 Nov 18.
5
Granulocytic sarcoma: a systematic review.粒细胞肉瘤:一项系统综述
Am J Blood Res. 2013 Dec 18;3(4):265-70.
6
MRI for evaluation of myeloid sarcoma in adults: a single-institution 10-year experience.MRI 用于评估成人骨髓肉瘤:单机构 10 年经验。
AJR Am J Roentgenol. 2012 Dec;199(6):1193-8. doi: 10.2214/AJR.12.9057.
7
Wolf in sheep's clothing: acute chloroma disguised as a subdural hematoma.披着羊皮的狼:急性髓细胞白血病伪装成硬脑膜下血肿。
Neurocrit Care. 2012 Feb;16(1):148-50. doi: 10.1007/s12028-011-9631-7.
8
Granulocytic sarcoma of the spine: MRI and clinical review.脊柱粒细胞肉瘤:MRI 与临床复习。
AJR Am J Roentgenol. 2010 Feb;194(2):485-9. doi: 10.2214/AJR.09.3086.
9
Granulocytic Sarcoma in the Head and Neck: CT and MR Imaging Findings.头颈部粒细胞肉瘤:CT 和 MR 成像表现。
Clin Exp Otorhinolaryngol. 2009 Jun;2(2):66-71. doi: 10.3342/ceo.2009.2.2.66. Epub 2009 Jun 27.
10
Acute monoblastic leukemia with t(10;11)(p12;q23) presenting with pulmonary involvement: a case report and literature review.伴有t(10;11)(p12;q23)且出现肺部受累的急性单核细胞白血病:一例报告及文献复习
J Med Assoc Thai. 2008 Apr;91(4):559-63.

解析绿色瘤:影像学表现综述

Unravelling chloroma: review of imaging findings.

作者信息

Singh Anuradha, Kumar Pawan, Chandrashekhara Sheragaru Hanumanthappa, Kumar Atin

机构信息

Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Br J Radiol. 2017 Jul;90(1075):20160710. doi: 10.1259/bjr.20160710. Epub 2017 May 23.

DOI:10.1259/bjr.20160710
PMID:28445074
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5594979/
Abstract

Chloroma refers to the extramedullary proliferation of immature myeloid precursors occurring in a gamut of myeloproliferative and myelodysplastic conditions; acute myeloid leukaemia being the commonest. With non-specific clinical and imaging manifestations, it runs a high risk of misdiagnosis which may significantly affect the outcome of an otherwise treatable lesion. Also with these lesions heralding impending blast crises, awareness of the imaging findings becomes imperative. Imaging not only helps raise the suspicion but also guides further confirmation by demonstration of specific immunohistochemistry markers, ensuring timely institution of chemotherapy. In general, solid enhancing lesions in any haematological disorder could be chloromas, especially if multifocal with mass effect.

摘要

绿色瘤是指在一系列骨髓增殖性疾病和骨髓增生异常综合征中出现的未成熟髓系前体细胞的髓外增殖;急性髓系白血病是最常见的病因。由于其临床表现和影像学表现不具特异性,误诊风险很高,这可能会显著影响原本可治疗病变的预后。此外,这些病变预示着即将发生原始细胞危象,因此了解其影像学表现至关重要。影像学不仅有助于提高怀疑度,还能通过显示特定的免疫组化标志物来指导进一步确诊,确保及时进行化疗。一般来说,任何血液系统疾病中出现的实性强化病变都可能是绿色瘤,尤其是伴有占位效应的多灶性病变。